Document Detail


Prostaglandins E and F in amniotic fluid during stretch-induced cervical softening and labor at term.
MedLine Citation:
PMID:  6873748     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
An unspecified region of the uterus of 7 healthy pregnant patients at term, not yet in labor, was mechanically distended by extraamniotic application of rubber bougies. In all cases, significant onset of labor was noted within 20 min to 5 h, cervical softening progressed with time, and delivery was achieved within 21 h. Significant elevation of prostaglandin E (PGE) and F (PGF) levels in amniotic fluid was noted with the progress of cervical dilatation. It appears that the release of PGE and PGF is dependent on uterine stretching and/or the subsequently induced uterine contractions. A possible source of the release of PG in the present study was discussed.
Authors:
Y Manabe; T Okazaki; A Takahashi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Gynecologic and obstetric investigation     Volume:  15     ISSN:  0378-7346     ISO Abbreviation:  Gynecol. Obstet. Invest.     Publication Date:  1983  
Date Detail:
Created Date:  1983-09-23     Completed Date:  1983-09-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7900587     Medline TA:  Gynecol Obstet Invest     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  343-50     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Amniotic Fluid / metabolism*
Cervix Uteri / physiology*
Dilatation
Female
Humans
Labor, Induced / methods*
Mechanoreceptors / physiology
Myometrium / metabolism
Pregnancy
Prostaglandins E / metabolism*
Prostaglandins F / metabolism*
Chemical
Reg. No./Substance:
0/Prostaglandins E; 0/Prostaglandins F

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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