Document Detail

Prostaglandin vaginal suppositories: a simple and safe approach to the induction of labor.
MedLine Citation:
PMID:  6946350     Owner:  NLM     Status:  MEDLINE    
The results of 1000 consecutive unselected cases of induction of labor for medical or obstetric reasons using prostaglandin E2 suppositories are presented. The overall rate of failed induction resulting in a cesarean section in those patients with an unfavorable cervix has fallen from 42 to 2.5%. Only 27% of the entire series required augmentation of labor with intravenous oxytocin, the range being from 9.9% of multigravidas with a favorable cervix to 42.4% of primigravidas with an unfavorable cervix. Both low- and high-risk pregnancies are suitable for induction by this method and trials of vaginal breech delivery and of uterine scars have been safely and successfully carried out. This method has now become routine for the induction of labor at the authors' institution. It has proved to be simple, safe, and highly acceptable to patients and obstetricians alike in all cases in which a simple amniotomy would not suffice.
J H Shepherd; M J Bennett; D Laurence; F Moore; C D Sims
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  58     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  1981 Nov 
Date Detail:
Created Date:  1982-01-09     Completed Date:  1982-01-09     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  596-600     Citation Subset:  AIM; IM    
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MeSH Terms
Delivery, Obstetric / methods
Evaluation Studies as Topic
Fetal Monitoring
Labor, Induced / methods*
Oxytocin / administration & dosage
Prostaglandins E / administration & dosage*
Reg. No./Substance:
0/Prostaglandins E; 0/Suppositories; 363-24-6/Dinoprostone; 50-56-6/Oxytocin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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