Document Detail


Prostaglandin E2 excretion in spinal cord injury patients.
MedLine Citation:
PMID:  6587004     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Hyponatremia has proven to be a common finding in spinal cord injured (SCI) patients. Mechanisms exist whereby SCI patients with either normal or impaired renal function may develop it. One such mechanism may be an impairment in prostaglandin (PGE2) excretion resulting in unopposed activity of antidiuretic hormone (ADH). Paired 24-hour urine collections for PGE2 were collected from SCI patients with varying degrees of renal dysfunction. There was a wide interpatient variability in the excretion of PGE2, with no significant correlation of PGE2 excretion in respect to either urine volume, urine sodium concentration, or the degree of renal dysfunction.
Authors:
D A Sica; M Midha; E T Zawada; M Johnson; R W Hussey; W K Stacy
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of the American Paraplegia Society     Volume:  7     ISSN:  0195-2307     ISO Abbreviation:  J Am Paraplegia Soc     Publication Date:  1984 Apr 
Date Detail:
Created Date:  1984-07-10     Completed Date:  1984-07-10     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8303486     Medline TA:  J Am Paraplegia Soc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  27-30     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Creatinine / urine
Dinoprostone
Humans
Middle Aged
Prostaglandins E / urine*
Radioimmunoassay
Sodium / urine
Spinal Cord Injuries / urine*
Chemical
Reg. No./Substance:
0/Prostaglandins E; 363-24-6/Dinoprostone; 60-27-5/Creatinine; 7440-23-5/Sodium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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