Document Detail


Prostaglandin E2 and F2 alpha levels in the duodenal and antral mucosa of non-ulcer dyspeptic and duodenal ulcer patients.
MedLine Citation:
PMID:  2341116     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In the present study we evaluated the contents of endogenous prostaglandins type E2 and F2 alpha in the antral mucosa, and the type E2 in the duodenal mucosa in a group of thirty non-ulcer dyspeptics in comparison with a group of thirty duodenal ulcer patients. A significantly reduced concentration of duodenal and antral PGE2 was found in ulcer patients as compared with dyspeptic subjects. A significantly increased concentration of antral PGE2 was observed in cases with active superficial antral gastritis, either in dyspeptics or in duodenal ulcer patients, as compared with normal antrum cases. A significantly increased level of PGF2 alpha was found in active superficial gastritis of the dyspeptic group.
Authors:
M C Parodi; M Marugo; G Ciancamerla; R Santucci; L Fazzuoli
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Hepato-gastroenterology     Volume:  37     ISSN:  0172-6390     ISO Abbreviation:  Hepatogastroenterology     Publication Date:  1990 Apr 
Date Detail:
Created Date:  1990-06-28     Completed Date:  1990-06-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8007849     Medline TA:  Hepatogastroenterology     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  208-11     Citation Subset:  IM    
Affiliation:
Dept. of Gastroenterology, S. Martino Hospital, Genoa, Italy.
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MeSH Terms
Descriptor/Qualifier:
Adult
Dinoprost / metabolism*
Dinoprostone / metabolism*
Duodenal Ulcer / metabolism*
Duodenum / metabolism*
Dyspepsia / metabolism*
Female
Gastric Acid / secretion
Humans
Intestinal Mucosa / metabolism*
Male
Middle Aged
Pyloric Antrum / metabolism*
Chemical
Reg. No./Substance:
363-24-6/Dinoprostone; 551-11-1/Dinoprost

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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