Document Detail

Prospective study of infantile hemangiomas: demographic, prenatal, and perinatal characteristics.
MedLine Citation:
PMID:  17307549     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To characterize demographic, prenatal, and perinatal features of patients with infantile hemangiomas and to determine the importance of these factors in predicting rates of complication and treatment. STUDY DESIGN: We conducted a prospective study at 7 U.S. pediatric dermatology clinics. A consecutive sample of 1058 children, aged 12 years and younger, with infantile hemangiomas was enrolled between September 2002 and October 2003. A standardized questionnaire was used to collect demographic, prenatal, perinatal, and hemangioma-specific data. National Vital Statistic System Data (NVSS) was used to compare demographic variables and relevant rates of prenatal events. RESULTS: In comparison with the 2002 United States National Vital Statistics System birth data, we found that infants with hemangiomas were more likely to be female, white non-Hispanic, premature (P < .0001) and the product of a multiple gestation (10.6% versus 3.1%; P < .001). Maternal age was significantly higher (P < .0001), and placenta previa (3.1%) and pre-eclampsia (11.8%) were more common. CONCLUSIONS: Infants with hemangiomas are more likely to be female, white non-Hispanic, premature, and products of multiple gestations. Prenatal associations include older maternal age, placenta previa, and pre-eclampsia. No demographic, prenatal, and perinatal factors predicted higher rates of complications or need for treatment.
; Anita N Haggstrom; Beth A Drolet; Eulalia Baselga; Sarah L Chamlin; Maria C Garzon; Kimberly A Horii; Anne W Lucky; Anthony J Mancini; Denise W Metry; Brandon Newell; Amy J Nopper; Ilona J Frieden
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Publication Detail:
Type:  Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of pediatrics     Volume:  150     ISSN:  1097-6833     ISO Abbreviation:  J. Pediatr.     Publication Date:  2007 Mar 
Date Detail:
Created Date:  2007-02-19     Completed Date:  2007-03-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375410     Medline TA:  J Pediatr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  291-4     Citation Subset:  AIM; IM    
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MeSH Terms
Age Distribution
Child, Preschool
Fetal Diseases / diagnosis,  epidemiology
Follow-Up Studies
Hemangioma / congenital*,  epidemiology*,  physiopathology
Infant, Newborn
Maternal Age
Perinatal Care
Prenatal Diagnosis
Prospective Studies
Risk Assessment
Sex Distribution
Skin Neoplasms / congenital*,  epidemiology*,  physiopathology
Socioeconomic Factors
United States / epidemiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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