| Prospective randomized study of viscous lidocaine versus benzocaine in a GI cocktail for dyspepsia. | |
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MedLine Citation:
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PMID: 15219296 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We hypothesized that Benzocaine (Hurricaine) would work as quickly and effectively as viscous Lidocaine in this preparation. This was a prospective randomized, single-blinded comparison between Benzocaine and Lidocaine as the topical anesthetic in a gastrointestinal (GI) cocktail. Patients 18 years or older were approached for participation when a GI cocktail was ordered by the Emergency Physician. Patients were randomized to equivalent doses of either Benzocaine or viscous Lidocaine in addition to 30 cc of Maalox and 10 cc of Donnatal. Assessment using a visual analog pain scale occurred at time intervals of 0, 5, 15, and 30 min. Eighty-two patients were enrolled (44 to Benzocaine, 38 to viscous Lidocaine), with each group having a statistically significant improvement in pain (p < 0.001). There were no statistical differences between the Benzocaine and viscous Lidocaine groups in terms of the relief of symptoms at each of the assessment times. There were no adverse outcomes in either group. |
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Authors:
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Gary M Vilke; Albert Jin; Daniel P Davis; Theodore C Chan |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: The Journal of emergency medicine Volume: 27 ISSN: 0736-4679 ISO Abbreviation: J Emerg Med Publication Date: 2004 Jul |
Date Detail:
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Created Date: 2004-06-28 Completed Date: 2004-11-16 Revised Date: 2009-10-05 |
Medline Journal Info:
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Nlm Unique ID: 8412174 Medline TA: J Emerg Med Country: United States |
Other Details:
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Languages: eng Pagination: 7-9 Citation Subset: IM |
Affiliation:
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Department of Emergency Medicine, University of California-San Diego Medical Center, 200 West Arbor Drive, Mailcode #8676, San Diego, CA 92103, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aluminum Hydroxide / administration & dosage Anesthetics, Local / administration & dosage* Antacids / administration & dosage Atropine / administration & dosage Benzocaine / administration & dosage* Drug Combinations Drug Therapy, Combination Dyspepsia / drug therapy* Female Humans Lidocaine / administration & dosage* Magnesium Hydroxide / administration & dosage Male Phenobarbital / administration & dosage Prospective Studies Scopolamine / administration & dosage Simethicone / administration & dosage Single-Blind Method Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Anesthetics, Local; 0/Antacids; 0/Donnatal; 0/Drug Combinations; 0/aluminum hydroxide, magnesium hydroxide, simethicone drug combination; 1309-42-8/Magnesium Hydroxide; 137-58-6/Lidocaine; 21645-51-2/Aluminum Hydroxide; 50-06-6/Phenobarbital; 51-34-3/Scopolamine; 51-55-8/Atropine; 8050-81-5/Simethicone; 94-09-7/Benzocaine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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