| Prospective randomized study of endovenous radiofrequency obliteration (closure procedure) versus ligation and stripping in a selected patient population (EVOLVeS Study). | |
| | |
MedLine Citation:
|
PMID: 12891099 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
PURPOSE: This study was designed as a prospective multicenter randomized comparison of procedure-related complications, patient recuperation, and quality-of-life outcomes between patients undergoing vein stripping with high ligation and patients undergoing great saphenous vein (GSV) obliteration with temperature-controlled radiofrequency ablation without adjunctive high ligation (Closure procedure). METHODS: Eighty-five patients (86 limbs) from five sites (France, 2; Austria, 1; United States, 2) were randomly allocated to undergo radiofrequency obliteration (RFO) or stripping and high ligation (S&L). Final analysis included data for 44 limbs in the RFO group and 36 limbs in the S&L group. Follow-up examinations were performed at 72 hours, 1 week, 3 weeks, and 4 months. All patients completed the CIVIQ2 quality-of-life (QOL) questionnaire and underwent clinical and ultrasound examinations at each follow-up visit. RESULTS: Immediate success on the day of treatment was reported for 95% (42 of 44) of limbs in the RFO group and 100% (36 of 36) of limbs in the S&L group. In seven RFO limbs (16.3%) a scan obtained 72 hours after the procedure showed flow in the proximal GSV. Five of these segments had reflux in the open segment. At 1 week two of these closed, and an additional segment closed at 3 weeks. In no cases did flow reappear after complete occlusion of the GSV. Time to return to normal activities was significantly less in the RFO group (mean, 1.15 days; 95% confidence interval [CI], 0.05-2.34) compared with the S&L group (mean, 3.89 days; CI, 2.67-5.12; P =.02). In the RFO group, 80.5% of patients returned to routine activities of daily living within 1 day, compared with 46.9% of patients in the S&L group (P <.01). Patients in the RFO group were able to return to work in 4.7 days (CI, 1.16-8.17), compared with 12.4 days (CI, 8.66-16.23) for the S&L group (P <.05). Analysis of the QOL surveys showed statistically significant differences in favor of the RFO group for global score and pain score during follow-up. The magnitude of the difference, however, progressively decreased between 1 week and 4 months. CONCLUSIONS: In the absence of significant complications, such as deep vein thrombosis and pulmonary embolism, severe neuritic sequelae, and skin burns, there are significant early advantages to endovascular obliteration of the GSV compared with conventional vein stripping. |
| | |
Authors:
|
F Lurie; D Creton; B Eklof; L S Kabnick; R L Kistner; O Pichot; S Schuller-Petrovic; C Sessa |
Related Documents
:
|
7850539 - Functional morbidity of hyperthermic isolated regional perfusion of the extremities. 15683259 - Preliminary results after application of absorbable metal stents in patients with criti... 16494189 - Devastating consequences of subway accidents: traumatic amputations. 8411469 - Surgery for chronic lower extremity ischemia in patients eighty or more years of age: o... 16427339 - Thrombolysis for acute lower limb ischaemia--a prospective, randomised, multicentre stu... 8284579 - Ischemic rest pain of the lower extremities. treatment with peripheral nerve crush. 22378659 - Active comparator-controlled, rater-blinded study of corticotropin-based immunotherapie... 20690869 - Effect of stretch positions on hamstring muscle length, lumbar flexion range of motion,... 17903569 - Effectiveness of hypopharyngeal packing during nasal and sinus surgery in the preventio... |
Publication Detail:
|
Type: Clinical Trial; Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Journal of vascular surgery Volume: 38 ISSN: 0741-5214 ISO Abbreviation: J. Vasc. Surg. Publication Date: 2003 Aug |
Date Detail:
|
Created Date: 2003-07-31 Completed Date: 2003-09-04 Revised Date: 2012-10-03 |
Medline Journal Info:
|
Nlm Unique ID: 8407742 Medline TA: J Vasc Surg Country: United States |
Other Details:
|
Languages: eng Pagination: 207-14 Citation Subset: IM |
Affiliation:
|
Straub Foundation, Straub Clinic and Hospital, 1100 Ward Avenue, Suite 1045, Honolulu, HI 96814, USA. tedlurie@yahoo.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Catheter Ablation / adverse effects*, methods* Female Humans Male Middle Aged Postoperative Complications Prospective Studies Quality of Life Recovery of Function Saphenous Vein / surgery* Treatment Outcome Varicose Veins / surgery* Vascular Surgical Procedures / adverse effects*, methods*, rehabilitation |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Bright cyclic rearing protects albino mouse retina against acute light-induced apoptosis.
Next Document: Open surgical and endovascular treatment of superior vena cava syndrome caused by nonmalignant disea...