Document Detail


Prospective, randomized study comparing highly purified urinary follicle-stimulating hormone (FSH) and recombinant FSH for in vitro fertilization/intracytoplasmic sperm injection in patients with polycystic ovary syndrome.
MedLine Citation:
PMID:  20188364     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In a randomized study comparing purified urinary FSH with recombinant FSH for IVF/intracytoplasmic sperm injection in patients with polycystic ovary syndrome, there was no significant difference between the mean total dose of FSH used, duration of stimulation, number of retrieved oocytes, number of mature oocytes, number of embryos transferred, or the ongoing pregnancy rate between the two groups. However, there were significantly more fertilized oocytes, a higher fertilization rate, more top-quality embryos, and more cryopreserved embryos in the urinary FSH group.
Authors:
Mohamed Aboulghar; Waleed Saber; Yahia Amin; Mona Aboulghar; Ragaa Mansour; Gamal Serour
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Publication Detail:
Type:  Comparative Study; Journal Article; Randomized Controlled Trial     Date:  2010-02-26
Journal Detail:
Title:  Fertility and sterility     Volume:  94     ISSN:  1556-5653     ISO Abbreviation:  Fertil. Steril.     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-10-27     Completed Date:  2010-12-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2332-4     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
Affiliation:
Department of Obstetrics and Gynecology, Faculty of Medicine, Cairo University, Cairo, Egypt. ghar@link.net
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MeSH Terms
Descriptor/Qualifier:
Adult
Female
Fertilization in Vitro / methods*
Follicle Stimulating Hormone / adverse effects,  therapeutic use*
Humans
Infertility, Female / drug therapy*,  etiology
Ovarian Hyperstimulation Syndrome / prevention & control
Ovulation Induction / methods
Polycystic Ovary Syndrome / complications,  drug therapy*
Pregnancy
Pregnancy Rate
Recombinant Proteins / adverse effects,  therapeutic use
Sperm Injections, Intracytoplasmic / methods
Treatment Outcome
Urofollitropin / adverse effects,  isolation & purification,  therapeutic use*
Young Adult
Chemical
Reg. No./Substance:
0/Recombinant Proteins; 0/Urofollitropin; 9002-68-0/Follicle Stimulating Hormone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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