| Prospective randomized evaluation of stentless vs. stented aortic biologic prosthetic valves in the elderly at five years. | |
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MedLine Citation:
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PMID: 19126556 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: Randomized trials comparing stentless to stented bioprostheses for aortic valve replacement in elderly are scarce. The aim of this study was early and mid-term evaluation of these bioprostheses, with regards to clinical outcome and hemodynamic performance. METHODS: Between September 1999 and January 2001, 40 patients with aortic stenosis, over the age of 75 years, were randomly assigned to receive either the stented Perimount (n=20) or the stentless Prima Plus (n=20) bioprosthesis. Clinical outcomes, left ventricular mass regression, effective orifice area, ejection fraction and mean gradients were evaluated at discharge, six months, one year and five years after surgery. RESULTS: At five years, there were 5/20 (25%) deaths in the stentless group and 6/20 (30%) deaths in the stented group (all non-valve-related). There was one case of endocarditis in each group, early postoperatively. Overall, a significant decrease in left ventricular mass was found five years postoperatively. However, there was no significant difference in the rate and completeness of LV-mass regression between the groups (LV mass index 114+/-34.1 vs. 120+/-27.2). Furthermore, hemodynamic performance of the valves (mean gradient of 9.9+/-4.8 mmHg vs. 10.2+/-4.2 mmHg) did not differ significantly between the groups. CONCLUSIONS: At five years, stentless valves were not superior to the stented valves, with regards to hemodynamic performance, regression of left ventricular mass and clinical outcome. |
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Authors:
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Petar S Risteski; Sven Martens; Amin Rouhollahpour; Gerhard Wimmer-Greinecker; Anton Moritz; Mirko Doss |
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Publication Detail:
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Type: Comparative Study; Journal Article; Randomized Controlled Trial Date: 2009-01-06 |
Journal Detail:
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Title: Interactive cardiovascular and thoracic surgery Volume: 8 ISSN: 1569-9285 ISO Abbreviation: Interact Cardiovasc Thorac Surg Publication Date: 2009 Apr |
Date Detail:
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Created Date: 2009-03-23 Completed Date: 2009-06-25 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101158399 Medline TA: Interact Cardiovasc Thorac Surg Country: England |
Other Details:
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Languages: eng Pagination: 449-53 Citation Subset: IM |
Affiliation:
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Department of Thoracic and Cardiovascular Surgery, Johann Wolfgang Goethe University, Frankfurt am Main, Germany. docpsr@yahoo.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Aged, 80 and over Aortic Valve Stenosis / complications, physiopathology, surgery*, ultrasonography Bioprosthesis* Female Heart Valve Prosthesis* Heart Valve Prosthesis Implantation / adverse effects, instrumentation* Hemodynamics Humans Hypertrophy, Left Ventricular / etiology, ultrasonography Male Prospective Studies Prosthesis Design Stents* Time Factors Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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