| Prospective observational study of primary angioplasty of the infarct-related artery for acute myocardial infarction. | |
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MedLine Citation:
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PMID: 10407544 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Primary angioplasty has been shown to reduce rates of in-hospital mortality, recurrent ischaemia and infarction. However, the role of primary stenting and abciximab is presently undergoing evaluation. This study attempted to examine the feasibility, safety and outcomes of primary angioplasty in the treatment of acute myocardial infarction. Data in 100 patients who underwent primary angioplasty for evolving acute myocardial infarction was prospectively analysed to assess the safety and efficacy of various modalities. Twenty patients were in Killip class III and above. Multivessel (2 or more vessels) disease was noted in more than 52 cases. Procedural success was 99 percent; 86 patients received primary stenting, majority of them had Kalam-Raju stent implantation. Adjunct treatment included abciximab infusion in 22 and intra-aortic balloon pump support in 12. Overall mortality rate was six percent with a mortality of 2.2 percent in non-cardiogenic shock patients. Recurrent ischaemic events were noted in five, three of them had successful reperfusion with repeat angioplasty. None of the patients had emergency coronary artery bypass surgery. It is concluded that primary angioplasty is safe and effective with high procedural success. Recurrent ischaemic events are low, possibly due to routine use of stenting and selective use of abciximab. |
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Authors:
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N K Reddy; P R Raju; S Kapoor; M S Rao; R P Reddy; B K Sastry; B S Raju |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Indian heart journal Volume: 51 ISSN: 0019-4832 ISO Abbreviation: Indian Heart J Publication Date: 1999 Mar-Apr |
Date Detail:
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Created Date: 1999-08-03 Completed Date: 1999-08-03 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0374675 Medline TA: Indian Heart J Country: INDIA |
Other Details:
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Languages: eng Pagination: 167-72 Citation Subset: IM |
Affiliation:
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Department of Cardiology, CARE Hospital, Hyderabad. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Angioplasty, Transluminal, Percutaneous Coronary* Antibodies, Monoclonal / therapeutic use Anticoagulants / therapeutic use Coronary Angiography Feasibility Studies Female Hemodynamics Humans Immunoglobulin Fab Fragments / therapeutic use Male Middle Aged Myocardial Infarction / physiopathology, radiography, therapy* Prospective Studies Recurrence Stents Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Monoclonal; 0/Anticoagulants; 0/Immunoglobulin Fab Fragments; 143653-53-6/abciximab |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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