Document Detail


Prospective observational study of primary angioplasty of the infarct-related artery for acute myocardial infarction.
MedLine Citation:
PMID:  10407544     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Primary angioplasty has been shown to reduce rates of in-hospital mortality, recurrent ischaemia and infarction. However, the role of primary stenting and abciximab is presently undergoing evaluation. This study attempted to examine the feasibility, safety and outcomes of primary angioplasty in the treatment of acute myocardial infarction. Data in 100 patients who underwent primary angioplasty for evolving acute myocardial infarction was prospectively analysed to assess the safety and efficacy of various modalities. Twenty patients were in Killip class III and above. Multivessel (2 or more vessels) disease was noted in more than 52 cases. Procedural success was 99 percent; 86 patients received primary stenting, majority of them had Kalam-Raju stent implantation. Adjunct treatment included abciximab infusion in 22 and intra-aortic balloon pump support in 12. Overall mortality rate was six percent with a mortality of 2.2 percent in non-cardiogenic shock patients. Recurrent ischaemic events were noted in five, three of them had successful reperfusion with repeat angioplasty. None of the patients had emergency coronary artery bypass surgery. It is concluded that primary angioplasty is safe and effective with high procedural success. Recurrent ischaemic events are low, possibly due to routine use of stenting and selective use of abciximab.
Authors:
N K Reddy; P R Raju; S Kapoor; M S Rao; R P Reddy; B K Sastry; B S Raju
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Indian heart journal     Volume:  51     ISSN:  0019-4832     ISO Abbreviation:  Indian Heart J     Publication Date:    1999 Mar-Apr
Date Detail:
Created Date:  1999-08-03     Completed Date:  1999-08-03     Revised Date:  2013-05-24    
Medline Journal Info:
Nlm Unique ID:  0374675     Medline TA:  Indian Heart J     Country:  INDIA    
Other Details:
Languages:  eng     Pagination:  167-72     Citation Subset:  IM    
Affiliation:
Department of Cardiology, CARE Hospital, Hyderabad.
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MeSH Terms
Descriptor/Qualifier:
Adult
Angioplasty, Balloon, Coronary*
Antibodies, Monoclonal / therapeutic use
Anticoagulants / therapeutic use
Coronary Angiography
Feasibility Studies
Female
Hemodynamics
Humans
Immunoglobulin Fab Fragments / therapeutic use
Male
Middle Aged
Myocardial Infarction / physiopathology,  radiography,  therapy*
Prospective Studies
Recurrence
Stents
Treatment Outcome
Chemical
Reg. No./Substance:
0/Antibodies, Monoclonal; 0/Anticoagulants; 0/Immunoglobulin Fab Fragments; X85G7936GV/abciximab

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