Document Detail

Prospective nonrandomized trial of silver impregnated cuff central lines.
MedLine Citation:
PMID:  16548318     Owner:  NLM     Status:  MEDLINE    
Central venous lines were used to administer total parenteral nutrition at our institution. In an attempt to reduce line sepsis, silver impregnated cuff central lines (Hohn catheter) were adopted as standard of practice. Using a comprehensive morbidity and mortality database, 134 patients with Hohn catheters were compared to 252 patients who had polypropylene central line. The incidence of central line sepsis was increased with Hohn catheters to 23 of 134 (17.2%). This compared to 8 of 252 (3.2%) patients with polypropylene catheters (P < 0.0001). Also, an increased incidence of pulmonary embolism of 15 of 134 (11.2%) in patients with Hohn catheters was observed as compared to 2 of 252 (0.8%) with a polypropylene catheter (P < 0.0001). Insertion of Hohn catheters through the intrajugular vein was judged to be more difficult than polypropylene catheters. This may cause increased trauma to the vein resulting in a higher incidence of line infection and pulmonary embolism.
Robert L Alderman; Paul H Sugarbaker
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  International surgery     Volume:  90     ISSN:  0020-8868     ISO Abbreviation:  Int Surg     Publication Date:    2005 Sep-Oct
Date Detail:
Created Date:  2006-03-21     Completed Date:  2006-07-07     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0043524     Medline TA:  Int Surg     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  219-22     Citation Subset:  IM    
Washington Cancer Institute, Washington, District of Columbia 20010, USA.
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MeSH Terms
Catheterization, Central Venous / adverse effects,  instrumentation*
Infection Control / methods
Parenteral Nutrition, Total / instrumentation*
Peritoneal Neoplasms / surgery,  therapy
Prospective Studies
Pulmonary Embolism / etiology
Reg. No./Substance:
0/Polypropylenes; 7440-22-4/Silver

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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