Document Detail


Prospective motion correction for single-voxel 1H MR spectroscopy.
MedLine Citation:
PMID:  20806374     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Head motion during (1)H MR spectroscopy acquisitions may compromise the quality and reliability of in vivo metabolite measurements. Therefore, a three-plane image-based motion-tracking module was integrated into a single-voxel (1)H MR spectroscopy (point-resolved spectroscopy) sequence. A series of three orthogonal spiral navigator images was acquired immediately prior to the MR spectroscopy water suppression module in order to estimate head motion. By applying the appropriate rotations and translations, the MR spectroscopy voxel position can be updated such that it remains stationary with respect to the brain. Frequency and phase corrections were applied during postprocessing to reduce line width and restore coherent averaging. Spectra acquired during intentional head motion in 11 volunteers demonstrate reduced lipid contamination and increased spectral reproducibility when motion correction is applied.
Authors:
Brian Keating; Weiran Deng; J Cooper Roddey; Nathan White; Anders Dale; V Andrew Stenger; Thomas Ernst
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine     Volume:  64     ISSN:  1522-2594     ISO Abbreviation:  Magn Reson Med     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-08-31     Completed Date:  2011-01-25     Revised Date:  2011-09-13    
Medline Journal Info:
Nlm Unique ID:  8505245     Medline TA:  Magn Reson Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  672-9     Citation Subset:  IM    
Copyright Information:
2010 Wiley-Liss, Inc.
Affiliation:
Department of Medicine, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii 96813-2427, USA. brianrk@hawaii.edu
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MeSH Terms
Descriptor/Qualifier:
Algorithms*
Artifacts*
Biopolymers / analysis*
Brain Chemistry*
Head Movements*
Humans
Magnetic Resonance Spectroscopy / methods*
Protons
Grant Support
ID/Acronym/Agency:
1R01 DA021146/DA/NIDA NIH HHS; G12 RR003061-21/RR/NCRR NIH HHS; G12 RR003061-226716/RR/NCRR NIH HHS; G12 RR003061-235492/RR/NCRR NIH HHS; G12 RR003061-245406/RR/NCRR NIH HHS; K02 DA016991-04/DA/NIDA NIH HHS; K02 DA016991-05/DA/NIDA NIH HHS; K02-DA16991/DA/NIDA NIH HHS; R01 DA021146-01A1/DA/NIDA NIH HHS; R01 DA021146-02/DA/NIDA NIH HHS; R01 DA021146-03/DA/NIDA NIH HHS; U54 56883//PHS HHS; U54 NS056883-01A1/NS/NINDS NIH HHS; U54 NS056883-02/NS/NINDS NIH HHS; U54 NS056883-03/NS/NINDS NIH HHS
Chemical
Reg. No./Substance:
0/Biopolymers; 0/Protons
Comments/Corrections

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