Document Detail

Prospective longitudinal comparative study of health-related quality of life in patients treated with radical prostatectomy or permanent brachytherapy for prostate cancer.
MedLine Citation:
PMID:  19571899     Owner:  NLM     Status:  MEDLINE    
To determine health-related quality of life (HRQOL) after radical retropubic prostatectomy (RRP) or permanent prostate brachytherapy (BT), third party-conducted QOL surveys were prospectively compared. Between 2004 and 2005, 37 patients underwent RRP and 36 were treated with BT. A QOL survey consisting of the Medical Outcomes Study 36-Item Short Form (SF-36), the University of California, Los Angeles, Prostate Cancer Index (UCLA-PCI) and the International Prostate Symptoms Score (IPSS) was completed prospectively by a research coordinator at baseline, and at 1, 3, 6 and 12 months after treatment. The RRP patients scored well in general QOL except at 1 month after surgery, with their mental health better than at baseline by 6 months after surgery. Disease-specific QOL in RRP patients received a low score at 1 month for both urinary and sexual function, though urinary function rapidly recovered to baseline levels. BT patient QOL was not affected by the therapy except in the IPSS score. However, general and mental health scores in BT patients were inferior to those in RRP patients. This prospective study revealed differences in QOL after RRP and BT. These results will be helpful in making treatment decisions.
Makoto Kobuke; Takashi Saika; Yoshiko Nakanishi; Shin Ebara; Daisuke Manabe; Tatsuya Uesugi; Hiroyuki Nose; Ryoji Arata; Tomoyasu Tsushima; Yasutomo Nasu; Hiromi Kumon
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta medica Okayama     Volume:  63     ISSN:  0386-300X     ISO Abbreviation:  Acta Med. Okayama     Publication Date:  2009 Jun 
Date Detail:
Created Date:  2009-07-02     Completed Date:  2009-07-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0417611     Medline TA:  Acta Med Okayama     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  129-35     Citation Subset:  IM    
Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8530, Japan.
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MeSH Terms
Brachytherapy* / adverse effects,  psychology
Health Status
Longitudinal Studies
Middle Aged
Postoperative Complications
Prospective Studies
Prostatectomy* / adverse effects,  psychology
Prostatic Neoplasms* / psychology,  radiotherapy,  surgery
Quality of Life*
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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