Document Detail

Prospective evaluation of transnasal esophagogastroduodenoscopy: feasibility and study on performance and tolerance.
MedLine Citation:
PMID:  10049409     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: With a pediatric endoscope, esophagogastroduodenoscopy (EGD) can be performed via a nasal route in adults. To evaluate this new procedure, we conducted a randomized comparative study of the feasibility of diagnostic transnasal EGD and assessed the factors influencing its quality and tolerance (endoscope diameter or route). METHODS: Transnasal EGD was attempted in 100 patients to assess its feasibility. For the analysis of quality and tolerance, 150 patients were randomized as follows into 3 groups according to the route of examinations: (1) oral route with 9.8 mm diameter standard videoendoscope; (2) oral route with 6.0 mm diameter pediatric videoendoscope; (3) transnasal route with 6.0 mm diameter pediatric videoendoscope. The operator assessed the quality of examination by standard scores. Patients quantified pain intensity, nausea, and choking sensation. RESULTS: Transnasal EGD was feasible in 82% of patients. The quality of the examination was significantly lower with pediatric endoscope. No difference was noted concerning pain intensity, but nausea and choking sensation were significantly reduced when the nasal route was used. CONCLUSIONS: Transnasal EGD is feasible in the routine practice of diagnostic EGD. The nasal route, and not endoscope diameter (6.0 mm vs 9.8 mm diameter), is the determining factor that explains increased patient tolerance during transnasal EGD. Technical improvements in pediatric videoendoscopes are required.
J Dumortier; T Ponchon; J Y Scoazec; B Moulinier; F Zarka; P Paliard; R Lambert
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Gastrointestinal endoscopy     Volume:  49     ISSN:  0016-5107     ISO Abbreviation:  Gastrointest. Endosc.     Publication Date:  1999 Mar 
Date Detail:
Created Date:  1999-04-14     Completed Date:  1999-04-14     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0010505     Medline TA:  Gastrointest Endosc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  285-91     Citation Subset:  IM    
Departments of Digestive Diseases and Pathology, Hôpital Edouard Herriot, Lyon, France.
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MeSH Terms
Aged, 80 and over
Endoscopy, Digestive System / standards*
Feasibility Studies
Middle Aged
Patient Acceptance of Health Care
Prospective Studies
Comment In:
Gastrointest Endosc. 1999 Mar;49(3 Pt 1):395-8   [PMID:  10049430 ]
Gastrointest Endosc. 2000 Mar;51(3):377-8   [PMID:  10699798 ]
Gastrointest Endosc. 2000 Jun;51(6):772   [PMID:  10840329 ]

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