Document Detail

Prospective evaluation of diagnostic accuracy of gastrofiberscopic biopsy in diagnosis of gastric cancer.
MedLine Citation:
PMID:  2920367     Owner:  NLM     Status:  MEDLINE    
The accuracy of gastrofiberscopic biopsy in diagnosis of gastric malignancies has been evaluated by studying operative and postmorten findings and clinical follow-up data in linkages at Osaka Cancer Registry, Japan, after an average of 7.7 years. Satisfactory data were obtained in follow-ups of all 1331 patients examined. There were only 31 (3.7%) false-negative diagnoses of malignancy among 858 patients diagnosed as having benign lesions, and only three (0.6%) false-positive diagnoses among 473 patients diagnosed as having malignant tumors. The false-negative diagnoses were most frequent in cases of elevated types of early cancer, advanced cancer of type 4 and leiomyosarcoma, or in cases located in the posterior wall and in the antrum. The three benign lesions that were diagnosed as malignant by biopsy were all associated with active ulceration, indicating that care is necessary in taking biopsy specimens of ulcerated lesions. From these findings the sensitivity and specificity of the gastrofiberscopic biopsy method for detection of gastric malignancies were calculated to be 93.8% and 99.6%, respectively, and the overall accuracy for all the patients was 97.4%. These results reconfirm that gastrofiberscopic biopsy is very useful for diagnosis of gastric malignancies.
M Tatsuta; H Iishi; S Okuda; A Oshima; H Taniguchi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cancer     Volume:  63     ISSN:  0008-543X     ISO Abbreviation:  Cancer     Publication Date:  1989 Apr 
Date Detail:
Created Date:  1989-04-18     Completed Date:  1989-04-18     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0374236     Medline TA:  Cancer     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1415-20     Citation Subset:  AIM; IM    
Department of Gastrointestinal Oncology, Center for Adult Diseases, Osaka, Japan.
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MeSH Terms
Adenocarcinoma / pathology*
Diagnosis, Differential
False Negative Reactions
Fiber Optic Technology*
Leiomyosarcoma / pathology*
Middle Aged
Prospective Studies
Stomach Neoplasms / pathology*
Stomach Ulcer / pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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