| Prospective evaluation of atrial tachyarrhythmias in patients with interatrial block. | |
| | |
MedLine Citation:
|
PMID: 17027099 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
INTRODUCTION: Interatrial block (P-wave> or =110 ms) is clinically associated with left atrial enlargement and electromechanical dysfunction as well as atrial tachyarrhythmias. We prospectively evaluated the incidence of such arrhythmias, especially atrial fibrillation among patients with interatrial block over the course of 1 year. METHODS: 118 patients (aged 48 to 104 years; female 56.6%) who had been hospitalized between December 15, 2004 and January 14, 2005 were identified and divided into 3 groups based on their respective baseline electrocardiogram (interatrial block=41 patients, sinus non-interatrial block=51 patients and atrial tachyarrhythmia=24 patients). Patients were subsequently followed for 12 months for pertinent cardiovascular events (heart failure, peripheral embolism, transient ischemic attacks and stroke), atrial tachyarrhythmias (atrial fibrillation and atrial flutter) and death as endpoints. RESULTS: 19 patients (17.9%) had atrial fibrillation during the 12-month follow-up (sinus non-interatrial block group=4 [9.1%], interatrial block group=12 [29.3%] and atrial tachyarrhythmia group=3 [14.3%]). Coronary artery disease, hypertension, pre-existing atrial fibrillation history, dilated cardiomyopathy, atrioventricular valvular disease and interatrial block (age- and sex-adjusted hazard ratio=4.2; 95% confidence interval 1.2-14.4; p=0.02) were significantly associated with future events of atrial fibrillation. However, logistic regression analysis indicated that interatrial block was not an independent predictor of future atrial fibrillation whereas only history of pre-existing atrial tachyarrhythmias was (hazard ratio=23.6; 95% confidence interval 4.5-121.7; p=0.0002). CONCLUSION: Interatrial block may be associated with atrial fibrillation but in a 12-month period, does not appear to be an independent predictor of future atrial fibrillation. Continued prospective investigation of such a relationship is certainly warranted given its already known consequences. |
| | |
Authors:
|
Vignendra Ariyarajah; Jaxon Fernandes; Mark Kranis; Sirin Apiyasawat; Kristin Mercado; David H Spodick |
Related Documents
:
|
22225709 - Pacing transmural scar tissue reduces left ventricle reverse remodeling after cardiac r... 9692479 - Left atrial reduction for chronic atrial fibrillation associated with mitral valve dise... 8855419 - Surgery for atrial fibrillation. 14739729 - An update on electrical cardioversion of atrial fibrillation. 3131959 - Generalised angiosarcoma of the heart. 7598579 - Conversion of postischemic ventricular fibrillation with intraaortic infusion of potass... 19403339 - Symbolic analysis detects alterations of cardiac autonomic modulation in congestive hea... 1879219 - Verapamil and ventricular tachycardias. 22740819 - Acute reversible heart failure caused by coronary vasoconstriction due to continuous 5-... |
Publication Detail:
|
Type: Comparative Study; Journal Article Date: 2006-10-05 |
Journal Detail:
|
Title: International journal of cardiology Volume: 118 ISSN: 1874-1754 ISO Abbreviation: Int. J. Cardiol. Publication Date: 2007 Jun |
Date Detail:
|
Created Date: 2007-05-08 Completed Date: 2007-07-23 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8200291 Medline TA: Int J Cardiol Country: Netherlands |
Other Details:
|
Languages: eng Pagination: 332-7 Citation Subset: IM |
Affiliation:
|
Massachusetts Veterans' Epidemiology Research and Information Center (MAVERIC), Veterans' Affairs Boston Healthcare System, Boston, MA 02130, USA. vignendra@hotmail.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Age Distribution Aged Aged, 80 and over Atrial Fibrillation / diagnosis, epidemiology*, etiology* Atrial Flutter / diagnosis, epidemiology*, etiology* Electrocardiography Female Heart Function Tests Humans Incidence Male Middle Aged Probability Prognosis Prospective Studies Risk Assessment Severity of Illness Index Sex Distribution Sinoatrial Block / complications*, diagnosis Stroke Volume Survival Rate Tachycardia / diagnosis, epidemiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The ether lipid-deficient mouse: tracking down plasmalogen functions.
Next Document: Sildenafil therapy for pulmonary arterial hypertension associated with atrial septal defects.