| Prospective correlation of arterial vs venous blood gas measurements in trauma patients. | |
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MedLine Citation:
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PMID: 22169587 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The objective of this study is to assess if venous blood gas (VBG) results (pH and base excess [BE]) are numerically similar to arterial blood gas (ABG) in acutely ill trauma patients. METHODS: We prospectively correlated paired ABG and VBG results (pH and BE) in adult trauma patients when ABG was clinically indicated. A priori consensus threshold of clinical equivalence was set at ± less than 0.05 pH units and ± less than 2 BE units. We hypothesized that ABG results could be predicted by VBG results using a regression equation, derived from 173 patients, and validated on 173 separate patients. RESULTS: We analyzed 346 patients and found mean arterial pH of 7.39 and mean venous pH of 7.35 in the derivation set. Seventy-two percent of the paired sample pH values fell within the predefined consensus equivalence threshold of ± less than 0.05 pH units, whereas the 95% limits of agreement (LOAs) were twice as wide, at -0.10 to 0.11 pH units. Mean arterial BE was -2.2 and venous BE was -1.9. Eighty percent of the paired BE values fell within the predefined ± less than 2 BE units, whereas the 95% LOA were again more than twice as wide, at -4.4 to 3.9 BE units. Correlations between ABG and VBG were strong, at r(2) = 0.70 for pH and 0.75 for BE. CONCLUSION: Although VBG results do correlate well with ABG results, only 72% to 80% of paired samples are clinically equivalent, and the 95% LOAs are unacceptably wide. Therefore, ABG samples should be obtained in acutely ill trauma patients if accurate acid-base status is required. |
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Authors:
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Scott E Rudkin; Christopher A Kahn; Jennifer A Oman; Matthew O Dolich; Shahram Lotfipour; Stephanie Lush; Marla Gain; Charmaine Firme; Craig L Anderson; Mark I Langdorf |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't Date: 2011-12-12 |
Journal Detail:
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Title: The American journal of emergency medicine Volume: 30 ISSN: 1532-8171 ISO Abbreviation: Am J Emerg Med Publication Date: 2012 Oct |
Date Detail:
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Created Date: 2012-10-01 Completed Date: 2013-01-29 Revised Date: 2013-04-16 |
Medline Journal Info:
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Nlm Unique ID: 8309942 Medline TA: Am J Emerg Med Country: United States |
Other Details:
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Languages: eng Pagination: 1371-7 Citation Subset: IM |
Copyright Information:
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Copyright © 2012 Elsevier Inc. All rights reserved. |
Affiliation:
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Department of Emergency Medicine, University of California, Irvine, CA 92868, USA. srudkin@uci.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Aged, 80 and over Alkalosis / blood Arteries* Blood Gas Analysis / methods* Female Humans Hydrogen-Ion Concentration Injury Severity Score Male Middle Aged Prospective Studies Trauma Centers Veins* Wounds and Injuries / blood* Young Adult |
| Grant Support | |
ID/Acronym/Agency:
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M01 RR00827/RR/NCRR NIH HHS; UL1 TR000153/TR/NCATS NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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