Document Detail

Prospective controlled study of rectangular titanium cage fusion compared with iliac crest autograft fusion in anterior cervical discectomy.
MedLine Citation:
PMID:  16212329     Owner:  NLM     Status:  MEDLINE    
OBJECT: The complications of autogenous bone grafting compel spine surgeons to seek alternative methods for cervical spinal fusion. This prospective study was conducted to evaluate the safety and efficacy of using rectangular titanium cage fusion compared with the widely performed iliac crest autograft fusion. METHODS: A total of 36 patients with cervical disc disease in whom an anterior approach was indicated for discectomy were included in this prospective controlled study. The first 18 consecutive patients received iliac crest autograft; the next 18 consecutive patients received rectangular titanium cages. The intergroup demographic and clinical data were comparable. All patients attended follow up for 1 year. According to Odom criteria, 15 (83%) of 18 patients in both groups experienced good to excellent functional recovery. According to the Patient Satisfaction Index, 17 (94%) of 18 patients in both groups were satisfied. The evaluation of neck pain and arm pain did not indicate statistically significant differences between either group. Fusion was present after 1 year in 16 (89%) of 18 patients who received iliac crest autografts and in 15 (83%) of 18 patients who received rectangular titanium cages. In the autograft group, a pseudarthrosis was present in one patient and marked hip pain was observed in three patients. In the cage group, there was one case of temporary vocal cord paresis but no implant-related complications. CONCLUSIONS: The authors conclude that the use of titanium cages in anterior cervical discectomy constitutes a safe and efficient alternative to iliac crest bone autograft.
Dimitris Zevgaridis; Claudius Thomé; Joachim K Krauss
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Publication Detail:
Type:  Comparative Study; Controlled Clinical Trial; Journal Article     Date:  2002-01-15
Journal Detail:
Title:  Neurosurgical focus     Volume:  12     ISSN:  1092-0684     ISO Abbreviation:  Neurosurg Focus     Publication Date:  2002 Jan 
Date Detail:
Created Date:  2005-10-10     Completed Date:  2006-04-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  100896471     Medline TA:  Neurosurg Focus     Country:  United States    
Other Details:
Languages:  eng     Pagination:  E2     Citation Subset:  IM    
Department of Neurosurgery, University Hospital Mannheim, Mannheim, Germany.
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MeSH Terms
Cervical Vertebrae / radiography,  surgery*
Diskectomy / instrumentation,  methods*
Ilium / radiography,  surgery*
Internal Fixators*
Middle Aged
Prospective Studies
Spinal Fusion / instrumentation,  methods*
Statistics, Nonparametric
Transplantation, Autologous / methods
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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