| Prospective cohort study into post-disaster benzodiazepine use demonstrated only short-term increase. | |
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MedLine Citation:
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PMID: 17606175 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: Benzodiazepines are typically prescribed for anxiety and insomnia, two complaints often reported after disasters. Benzodiazepines can cause mental or physical dependence, especially when taken for a long time. This study aims at evaluating benzodiazepine use in a disaster-stricken community with the help of computer-based records. STUDY DESIGN AND SETTING: This prospective cohort study covers a period of 4 years. For every patient, predisaster baseline data are available. Multilevel regression is applied to study differences in benzodiazepine use in 496 patients whose children were involved in the Volendam café fire on January 1, 2001 compared with 1,709 community controls, and 4,530 patients from an unaffected cohort. RESULTS: In community controls and patients from the unaffected cohort, benzodiazepine use remained stable in the course of the years. In the first year postfire, parents of disaster victims were 1.58 times more likely to use benzodiazepines than community controls (95% confidence interval 1.13-2.23). With regard to long-term use, differences between community controls and parents were statistically nonsignificant. CONCLUSIONS: In the studied community, benzodiazepines were predominantly prescribed as a short-term intervention. Clinical guidelines that advocate a conservative prescription policy were well adhered to. |
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Authors:
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T Dorn; C J Yzermans; J van der Zee |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2007-03-26 |
Journal Detail:
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Title: Journal of clinical epidemiology Volume: 60 ISSN: 0895-4356 ISO Abbreviation: J Clin Epidemiol Publication Date: 2007 Aug |
Date Detail:
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Created Date: 2007-07-03 Completed Date: 2007-11-19 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 8801383 Medline TA: J Clin Epidemiol Country: England |
Other Details:
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Languages: eng Pagination: 795-802 Citation Subset: IM |
Affiliation:
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Netherlands Institute for Health Services Research (NIVEL), Otterstraat 118-124, P.O. Box 1568, 3500 BN Utrecht, the Netherlands. t.dorn@nivel.nl |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anti-Anxiety Agents / therapeutic use* Anxiety / drug therapy* Benzodiazepines / therapeutic use* Case-Control Studies Confidence Intervals Data Collection / methods Drug Administration Schedule Female Fires* Humans Male Middle Aged Parents Prospective Studies Regression Analysis Risk Sleep Initiation and Maintenance Disorders / drug therapy* Substance-Related Disorders / prevention & control |
| Chemical | |
Reg. No./Substance:
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0/Anti-Anxiety Agents; 12794-10-4/Benzodiazepines |
| Comments/Corrections | |
Erratum In:
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J Clin Epidemiol. 2007 Oct;60(10):1092 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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