| Prospective, blinded trial of whole-body magnetic resonance imaging versus computed tomography positron emission tomography in staging primary and recurrent cancer of the head and neck. | |
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MedLine Citation:
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PMID: 20537210 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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OBJECTIVES: To compare the use of computed tomography - positron emission tomography and whole-body magnetic resonance imaging for the staging of head and neck cancer. PATIENTS AND METHODS: From January to July 2009, 15 consecutive head and neck cancer patients (11 men and four women; mean age 59 years; age range 19 to 81 years) underwent computed tomography - positron emission tomography and whole-body magnetic resonance imaging for pre-therapeutic evaluation. All scans were staged, as per the American Joint Committee on Cancer tumour-node-metastasis classification, by two blinded consultant radiologists, in two sittings. Diagnoses were confirmed by histopathological examination of endoscopic biopsies, and in some cases whole surgical specimens. RESULTS: Tumour staging showed a 74 per cent concordance, node staging an 80 per cent concordance and metastasis staging a 100 per cent concordance, comparing the two imaging modalities. CONCLUSION: This study found radiological staging discordance between the two imaging modalities. Whole-body magnetic resonance imaging is an emerging staging modality with superior visualisation of metastatic disease, which does not require exposure to ionising radiation. |
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Authors:
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J P O'Neill; M Moynagh; E Kavanagh; T O'Dwyer |
Publication Detail:
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Type: Journal Article Date: 2010-06-11 |
Journal Detail:
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Title: The Journal of laryngology and otology Volume: 124 ISSN: 1748-5460 ISO Abbreviation: J Laryngol Otol Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-11-25 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8706896 Medline TA: J Laryngol Otol Country: England |
Other Details:
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Languages: eng Pagination: 1274-7 Citation Subset: AIM; IM |
Affiliation:
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Department of Otolaryngology, Head and Neck Surgery, The Mater Hospital, Dublin, Ireland. joneill@rcsi.ie |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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