| Prospective assessment of continuous intrathecal infusion of baclofen for spasticity caused by acquired brain injury: a preliminary report. | |
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MedLine Citation:
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PMID: 9285608 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Twelve consecutive patients with severe spasticity and hypertonia following acquired brain injury were treated with continuous intrathecal infusion of baclofen via an implanted, programmable infusion pump-catheter system for a minimum of 3 months. In every case intrathecal baclofen therapy resulted in a statistically significant reduction in upper- and lower-extremity tone, spasm frequency, and reflexes, contributing to improved functional abilities. There were no untoward side effects or complications associated with treatment. This preliminary assessment indicates that intrathecal administration of baclofen is effective in treating the disabling spasticity caused by acquired brain injury in selected patients. |
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Authors:
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J M Meythaler; A McCary; M N Hadley |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of neurosurgery Volume: 87 ISSN: 0022-3085 ISO Abbreviation: J. Neurosurg. Publication Date: 1997 Sep |
Date Detail:
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Created Date: 1997-09-16 Completed Date: 1997-09-16 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0253357 Medline TA: J Neurosurg Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 415-9 Citation Subset: AIM; IM |
Affiliation:
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Department of Physical Medicine and Rehabilitation, University of Alabama School of Medicine, Birmingham 35294, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Baclofen / administration & dosage* Brain Injuries / complications* Female Humans Infusions, Parenteral Injections, Spinal Male Muscle Relaxants, Central / administration & dosage* Muscle Spasticity / drug therapy*, etiology Prospective Studies Severity of Illness Index Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Muscle Relaxants, Central; 1134-47-0/Baclofen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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