Document Detail

Prospective assessment after pediatric cardiac ablation: demographics, medical profiles, and initial outcomes.
MedLine Citation:
PMID:  15250858     Owner:  NLM     Status:  MEDLINE    
INTRODUCTION: A multicenter prospective study was designed and implemented to assess the short- and longer-term results and risks associated with radiofrequency (RF) ablation in children. METHODS AND RESULTS: Patients recruited for the study were aged 0 to 16 years with supraventricular tachycardia due to accessory pathways or AV nodal reentrant tachycardia (AVNRT), excluding patients with nontrivial congenital heart disease. A national registry also was established, and contributing centers were encouraged to enroll all pediatric patients, aged 0 to 21 years, undergoing ablation at their center. This report summarizes acute results of these procedures. For analysis, subjects were divided into three groups: the prospective cohort (n = 481), cohort-eligible registry participants (n = 504), and not cohort eligible registry participants (n = 1,776). Prospectively enrolled cohort patients were similar to cohort-eligible patients in terms of demographic and other patient characteristics. Overall success rates for RF ablation were high (95.7%), with higher success rates for left-sided and particularly left free-wall pathways (97.8%) than right free-wall pathways (90.8%). Complications of both electrophysiologic study and RF ablation were infrequent (4.2% and 4.0%, respectively), and there were no deaths. AV block was uncommon overall (1.2%) and was limited to ablation in AVNRT (2.1%) and septal accessory pathways (3.0%). CONCLUSION: Despite the multicenter and prospective design, the study demonstrates high success rates and low complication rates, which are comparable to prior single-center retrospective studies. These results may serve as the current best benchmark for expected results in the pediatric population, aged 0 to 16 years, both in terms of acute success rates and the occurrence of complications.
George F Van Hare; Harold Javitz; Dorit Carmelli; J Philip Saul; Ronn E Tanel; Peter S Fischbach; Ronald J Kanter; Michael Schaffer; Ann Dunnigan; Steven Colan; Gerald Serwer;
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Publication Detail:
Type:  Journal Article; Multicenter Study; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of cardiovascular electrophysiology     Volume:  15     ISSN:  1045-3873     ISO Abbreviation:  J. Cardiovasc. Electrophysiol.     Publication Date:  2004 Jul 
Date Detail:
Created Date:  2004-07-14     Completed Date:  2004-11-16     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  9010756     Medline TA:  J Cardiovasc Electrophysiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  759-70     Citation Subset:  IM    
Department of Pediatrics, Division of Cardiology, Stanford University, Stanford, California 94304, USA.
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MeSH Terms
Catheter Ablation*
Electrocardiography, Ambulatory
Electrophysiologic Techniques, Cardiac
Outcome Assessment (Health Care)*
Postoperative Complications
Prospective Studies
Tachycardia, Supraventricular / physiopathology,  surgery*
Grant Support
R01 HL058620-03/HL/NHLBI NIH HHS; R01 HL058620-04/HL/NHLBI NIH HHS; R01 HL058620-05/HL/NHLBI NIH HHS; R01 HL058620-06/HL/NHLBI NIH HHS; R01-HL58620/HL/NHLBI NIH HHS
Comment In:
J Cardiovasc Electrophysiol. 2004 Jul;15(7):771-2   [PMID:  15250859 ]

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