| Prospective analysis of lipid profiles in persons with a spinal cord injury during and 1 year after inpatient rehabilitation. | |
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MedLine Citation:
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PMID: 18295633 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: To investigate the course of lipid profiles during and 1 year after inpatient rehabilitation of persons with spinal cord injury, and to determine which personal, lesion, and lifestyle characteristics influence the changes in lipid profiles over time and among subjects. DESIGN: Multilevel regression analysis of measurement points during and after rehabilitation. SETTING: Eight rehabilitation centers in The Netherlands. PARTICIPANTS: People with complete and incomplete paraplegia and tetraplegia (N=180). INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: Total cholesterol (TC), high-density lipoprotein (HDL), low-density lipoprotein (LDL), triglycerides (TG), and the TC/HDL ratio. RESULTS: We found a significant decrease in TG and TC/HDL during inpatient rehabilitation and a significant increase in HDL during and after inpatient rehabilitation. TC and LDL, however, showed unfavorable increases after clinical discharge. The changes in HDL and LDL over time differed between lesion groups. An increase in the body mass index (BMI) led to an unfavorable change in all lipid profiles. Older participants showed higher TC, LDL, and HDL concentrations. Women and participants who consumed some alcohol, or who were more active 1 year after discharge, had more favorable HDL levels. CONCLUSIONS: Lipid profiles improved during inpatient rehabilitation but deteriorated somewhat after clinical discharge. Controlling one's BMI seems important in diminishing the risk for unfavorable lipid profiles. |
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Authors:
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Sonja de Groot; Annet J Dallmeijer; Marcel W Post; Edmond L Angenot; Rita J van den Berg-Emons; Luc H van der Woude |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Archives of physical medicine and rehabilitation Volume: 89 ISSN: 1532-821X ISO Abbreviation: Arch Phys Med Rehabil Publication Date: 2008 Mar |
Date Detail:
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Created Date: 2008-02-25 Completed Date: 2008-03-12 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 2985158R Medline TA: Arch Phys Med Rehabil Country: United States |
Other Details:
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Languages: eng Pagination: 531-7 Citation Subset: AIM; IM |
Affiliation:
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Rehabilitation Center Amsterdam, Amsterdam, The Netherlands. s.de.groot@fbw.vu.nl |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Age Factors Aged Body Mass Index Cholesterol, HDL / blood Cohort Studies Humans Injury Severity Score Inpatients Life Style Lipids / blood* Male Middle Aged Multicenter Studies as Topic Multivariate Analysis Paraplegia / blood, rehabilitation Physical Therapy Modalities Predictive Value of Tests Probability Prospective Studies Quadriplegia / blood, rehabilitation Regression Analysis Rehabilitation Centers Spinal Cord Injuries / blood*, diagnosis*, rehabilitation* Time Factors Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Cholesterol, HDL; 0/Lipids |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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