| A Prospective Study on the use of the Indicator Test Neuropad® for the Early Diagnosis of Peripheral Neuropathy in type 2 Diabetes. | |
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MedLine Citation:
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PMID: 20690070 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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AIM: The aim of this prospective study was to evaluate the contribution of the indicator test for sudomotor function Neuropad (®) to the early diagnosis of peripheral neuropathy in patients with type 2 diabetes mellitus. Included were 109 type 2 diabetic patients (55 men, mean age 56.15±6.14 years), whose initial clinical examination (Neuropathy Disability Score, NDS) was negative for neuropathy. Patients were first examined between January and June 2004 and re-examined 5 years later by the NDS and Neuropad (®). Initially, 70 patients (64.22%) had normal and 39 (35.78%) patients had abnormal Neuropad (®) (groups A and B, respectively). NDS was significantly higher in group B on both examinations (p<0.001). On the second examination, 2 patients (2.86%) in group A and 10 patients (25.64%) in group B had developed neuropathy (p=0.001). Neuropad (®) had 83.33% sensitivity and 68.04% specificity for neuropathy. There was a modest but significant agreement (kappa=0.259, p<0.001) between Neuropad (®) and NDS for neuropathy. CONCLUSIONS: Among type 2 diabetic patients with normal NDS, development of neuropathy is significantly more frequent in those with abnormal Neuropad (®). These results suggest a potential utility of Neuropad (®) for the earlier diagnosis of neuropathy in type 2 diabetes. |
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Authors:
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N Papanas; K Papatheodorou; D Papazoglou; S Kotsiou; E Maltezos |
Publication Detail:
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Type: Journal Article Date: 2010-08-05 |
Journal Detail:
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Title: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association Volume: 119 ISSN: 1439-3646 ISO Abbreviation: Exp. Clin. Endocrinol. Diabetes Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-02-11 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9505926 Medline TA: Exp Clin Endocrinol Diabetes Country: Germany |
Other Details:
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Languages: eng Pagination: 122-5 Citation Subset: IM |
Copyright Information:
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© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York. |
Affiliation:
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Outpatient Clinic of Obesity, Diabetes and Metabolism in the Second Department of Internal Medicine, Democritus University of Thrace, Greece. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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