Document Detail


Prospective randomized trial of venous cardiac computed tomographic angiography for facilitation of cardiac resynchronization therapy.
MedLine Citation:
PMID:  20579305     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Cardiovascular computed tomographic angiography (CTA) can visualize the coronary veins. We sought to assess the ability of CTA to facilitate resynchronization therapy (CRT) procedures using a prospective randomized single-center pilot study.
METHODS: Patients underwent CTA for characterization of cardiomyopathy prior to biventricular implantable cardiac-defibrillator implant. Randomization was performed with operator review of the CTA for coronary venous anatomy prior to CRT in one-half of the cases. Invasive coronary venous angiograms were used in all procedures. Analysis included procedure times and utilization of contrast, fluoroscopy, and guide catheters.
RESULTS: Characteristics of the 26 patients enrolled were mean age 55 ± 11 years, male 76.9%, ischemic etiology 35%, ejection fraction 25 ± 3%, class III congestive heart failure 100%, and QRS duration 179 ± 29 ms. Of patients enrolled, 22 had both CTA and procedure initiation. Three patients (two with CTA review and one without CTA review) had aborted procedures due to hemodynamic issues. Analysis of the 22 patients (nine with preprocedure CTA review and 13 without CTA review) demonstrated that preprocedure review of CTA coronary venous anatomy led to significantly decreased procedure times and utilization of contrast, fluoroscopy, and guide catheters.
CONCLUSIONS: Preprocedure review of CTA coronary venous anatomy may lead to decreased procedural times and utilization of contrast, fluoroscopy, and guide catheters. These preliminary results will need to be evaluated in larger heart failure populations undergoing CRT.
Authors:
Marc J Girsky; Jerold S Shinbane; Naser Ahmadi; Songshou Mao; Ferdinand Flores; Matthew J Budoff
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Pacing and clinical electrophysiology : PACE     Volume:  33     ISSN:  1540-8159     ISO Abbreviation:  Pacing Clin Electrophysiol     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-09-30     Completed Date:  2011-02-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7803944     Medline TA:  Pacing Clin Electrophysiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1182-7     Citation Subset:  IM    
Copyright Information:
©2010, The Authors. Journal compilation ©2010 Wiley Periodicals, Inc.
Affiliation:
Division of Cardiology, Harbor-UCLA Research and Education Institute, 1124 W Carson Street, Torrance, CA 90502, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Cardiac Resynchronization Therapy / methods*
Cardiomyopathies / radiography,  therapy*
Coronary Angiography / methods*
Defibrillators, Implantable
Female
Heart Failure / radiography,  therapy*
Humans
Male
Middle Aged
Myocardial Ischemia / radiography,  therapy*
Pilot Projects
Prospective Studies
Stroke Volume
Tomography, X-Ray Computed / methods*
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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