Document Detail

Prospective Randomized Study of Marsupialization versus Silver Nitrate Application in the Management of Bartholin Gland Cysts and Abscesses.
MedLine Citation:
PMID:  19598336     Owner:  NLM     Status:  MEDLINE    
STUDY OBJECTIVE: To prospectively compare the efficacy of marsupialization or silver nitrate application in the treatment of Bartholin gland cysts abscesses, both of which are widely used as outpatient procedures. DESIGN: Prospective randomized trial. Design classification I. SETTING: Teaching and research hospital, a tertiary center. PATIENTS: A total of 212 patients admitted to our gynecology clinic with symptomatic Bartholin gland cysts/abscesses. INTERVENTIONS: Marsupialization and silver nitrate application in Bartholin gland cysts/abscesses. MEASUREMENTS AND MAIN RESULTS: In all, the 212 patients were randomly allocated to either marsupialization (group I) or silver nitrate application (group II) from March 2005 through March 2007. A total of 159 women were eligible for reevaluation at the end of the sixth month. In all, 83 were randomized to group I and 76 to group II. The patients were called for revisits at day 3, day 7, month 1, and month 6 of treatment. The 2 groups were compared for recurrence rates as primary outcome and duration of procedures, complications, size of scar tissues, and presence of dyspareunia as secondary outcomes. Comparisons of 2 groups were evaluated by Pearson X(2) test and Mann-Whitney U test, as appropriate. The 2 groups were comparable with regard to age, parity, and diameter of cyst or abscess. The recurrence rates were similar: 24.1% in group I and 26.3% in group II at 6 months (p =.67). No statistically significant differences were found in respect to duration of procedures or presence of dyspareunia. Complete healing without scar formation was observed in 31.3% and 55.7% of patients in groups I and II, respectively, and this was statistically significant (p =.007). CONCLUSION: Marsupialization and silver nitrate application seem to be equally effective management methods in Bartholin cyst and abscesses, however, silver nitrate favors complete healing with less scar formation.
Ozlem Ozdegirmenci; Fulya Kayikcioglu; Ali Haberal
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Journal of minimally invasive gynecology     Volume:  16     ISSN:  1553-4650     ISO Abbreviation:  -     Publication Date:    2009 Mar-Apr
Date Detail:
Created Date:  2009-07-13     Completed Date:  2009-08-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101235322     Medline TA:  J Minim Invasive Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  149-52     Citation Subset:  IM    
Ankara Etlik Maternity and Women's Health Teaching Research Hospital, Gynecology Clinic, Ankara, Turkey.
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MeSH Terms
Bartholin's Glands / surgery*
Cysts / surgery*
Middle Aged
Recurrence / prevention & control
Sclerosing Solutions / therapeutic use*
Silver Nitrate / therapeutic use*
Surgical Procedures, Minimally Invasive / methods*
Suture Techniques
Treatment Outcome
Wound Healing
Young Adult
Reg. No./Substance:
0/Sclerosing Solutions; 7761-88-8/Silver Nitrate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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