Document Detail

Prospective Characterization of Catheter-Tissue Contact Force at Different Anatomical Sites During Antral Pulmonary Vein Isolation.
MedLine Citation:
PMID:  23087399     Owner:  NLM     Status:  Publisher    
BACKGROUND: -Catheter-tissue contact is critical for effective lesion creation. We characterized the contact force (CF) at different anatomical sites during antral pulmonary vein isolation (PVI) for atrial fibrillation (AF). METHODS AND RESULTS: -Two experienced operators performed PVI in 22 patients facilitated by a novel CF-sensing ablation catheter in a blinded fashion. Average CF and force-time integral data from 1602 lesions were analyzed. The left and right PV antra were divided into: carina, superior, inferior, anterior and posterior quadrants for analysis. There was significant variability in CF within and between different PV quadrants (P <0.05). Lowest CF of all left PV sites was at the carina and anteriorly whereas highest CF was at the superior and inferior quadrants (P<0.05). Lowest CF of all right PV sites was at the carina whereas highest CF was at the anterior and inferior quadrants (P<0.05). When comparing similar PV quadrants on the left vs. right (e.g. left carina vs. right carina), CF was always higher in the right PVs (P<0.05), except at the superior quadrant, where CF was similar for the left and right PVs (P=0.19). There was no specific pattern of anatomic distribution of excess CF (P=0.39). CONCLUSIONS: -Monitoring of catheter-tissue CF during PVI demonstrates significant variability in CF within and between different PV antral sites. Sites of lowest CF were the carina and anterior left PVs and the carina of the right PVs. This information may be important for improving ablation efficacy and clinical outcomes during PVI.
Saurabh Kumar; Joseph B Morton; Justin Lee; Karen Halloran; Steven J Spence; Alexandra Gorelik; Graham Hepworth; Peter M Kistler; Jonathan M Kalman
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-19
Journal Detail:
Title:  Circulation. Arrhythmia and electrophysiology     Volume:  -     ISSN:  1941-3084     ISO Abbreviation:  Circ Arrhythm Electrophysiol     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101474365     Medline TA:  Circ Arrhythm Electrophysiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
1 RMH, Parkville & Univ of Melbourne, Victoria & Alfred Hosp and Baker IDI, Prahran, Australia;
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