| Propylthiouracil-induced hypersensitivity vasculitis presenting as respiratory failure. | |
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MedLine Citation:
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PMID: 1424898 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Hypersensitivity vasculitis associated with propylthiouracil therapy is a well-documented clinical entity. Although any organ system may be involved, it is most unusual for pulmonary manifestations to be the cardinal presenting features. We report a 72-year-old woman presenting with respiratory failure and hemoptysis following initiation of propylthiouracil therapy for Graves' disease. She had cutaneous stigmata of hypersensitivity vasculitis and diffuse pulmonary infiltrates. The infiltrates improved dramatically after discontinuation of the propylthiouracil therapy and initiation of intravenous corticosteroid therapy. |
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Authors:
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S J Stankus; N T Johnson |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Chest Volume: 102 ISSN: 0012-3692 ISO Abbreviation: Chest Publication Date: 1992 Nov |
Date Detail:
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Created Date: 1992-12-04 Completed Date: 1992-12-04 Revised Date: 2009-11-19 |
Medline Journal Info:
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Nlm Unique ID: 0231335 Medline TA: Chest Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1595-6 Citation Subset: AIM; IM |
Affiliation:
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Madigan Army Medical Center, Department of Family Practice, Fort Lewis, WA 98431-5000. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Female Humans Lung / radiography Propylthiouracil / adverse effects* Respiratory Insufficiency / etiology*, radiography Skin / pathology Vasculitis, Leukocytoclastic, Cutaneous / chemically induced*, complications*, pathology |
| Chemical | |
Reg. No./Substance:
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51-52-5/Propylthiouracil |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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