Document Detail

Propranolol for the treatment of hypertension in pregnancy.
MedLine Citation:
PMID:  656347     Owner:  NLM     Status:  MEDLINE    
Twenty-five women were treated with propranolol during 26 pregnancies complicated by hypertension. The fetal wastage, which had been 48 per cent before treatment with propranolol was reduced to 15.4 per cent, with one missed abortion and three stillbirths. Of the 22 liveborn infants 2 were small-for-dates but all 22 had Apgar scores of 9 or 10 at five minutes. There were no congenital anomalies in 25 viable infants and none of the 22 liveborn infants had clinical or laboratory evidence of hypoglycaemia. The blood pressure was controlled in 17 of 19 patients taking propranolol alone (40 to 160 mg/day) and in 6 of 7 taking propranolol with diuretics.
H E Eliahou; D S Silverberg; E Reisin; I Romem; S Mashiach; D M Serr
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British journal of obstetrics and gynaecology     Volume:  85     ISSN:  0306-5456     ISO Abbreviation:  Br J Obstet Gynaecol     Publication Date:  1978 Jun 
Date Detail:
Created Date:  1978-09-01     Completed Date:  1978-09-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7503752     Medline TA:  Br J Obstet Gynaecol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  431-6     Citation Subset:  AIM; IM    
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MeSH Terms
Apgar Score
Chlorthalidone / therapeutic use
Fetal Death
Hypertension / drug therapy*
Infant, Newborn
Infant, Small for Gestational Age
Pregnancy Complications, Cardiovascular / drug therapy*
Propranolol / therapeutic use*
Reg. No./Substance:
525-66-6/Propranolol; 77-36-1/Chlorthalidone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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