Document Detail


Propranolol treatment for hemangioma of infancy: risks and recommendations.
MedLine Citation:
PMID:  19840322     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Hemangioma of infancy is a condition that may be associated with significant morbidity. While evidence most supports the use of corticosteroids, there is no well-defined or Federal Drug Administration (FDA)-approved systemic therapy for hemangioma of infancy. All currently used treatments have significant risks. Dramatic improvement of complicated hemangioma of infancy to propranolol was recently reported, but details for initiating therapy, monitoring, and potential risks were not included. We present two infants treated with propranolol, who suffered complications and propose a treatment protocol to minimize potential adverse events.
Authors:
Leslie P Lawley; Elaine Siegfried; Jane L Todd
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric dermatology     Volume:  26     ISSN:  1525-1470     ISO Abbreviation:  Pediatr Dermatol     Publication Date:    2009 Sep-Oct
Date Detail:
Created Date:  2009-10-20     Completed Date:  2010-01-14     Revised Date:  2011-01-10    
Medline Journal Info:
Nlm Unique ID:  8406799     Medline TA:  Pediatr Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  610-4     Citation Subset:  IM    
Affiliation:
Department of Dermatology, Emory University School of Medicine, Atlanta, Georgia 30322, USA. lpotter@emory.edu
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MeSH Terms
Descriptor/Qualifier:
Adrenergic beta-Antagonists / administration & dosage*,  adverse effects*
Female
Hemangioma / drug therapy*,  epidemiology
Humans
Infant
Practice Guidelines as Topic
Propranolol / administration & dosage*,  adverse effects*
Risk Factors
Chemical
Reg. No./Substance:
0/Adrenergic beta-Antagonists; 525-66-6/Propranolol
Comments/Corrections
Comment In:
Pediatr Dermatol. 2010 Sep;27(5):558   [PMID:  21182650 ]
Pediatr Dermatol. 2010 May;27(3):319-20; author reply 320-1   [PMID:  20609165 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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