Document Detail

Propofol versus midazolam: safety and efficacy for sedating the severe trauma patient.
MedLine Citation:
PMID:  9620508     Owner:  NLM     Status:  MEDLINE    
IMPLICATIONS: In a prospective, controlled, randomized study, we confirmed the safety and efficacy of midazolam and propofol, alone or in combination, in the prolonged sedation of a homogeneous group of severe trauma patients, particularly in patients with head trauma. The propofol group had shorter wake-up times and higher triglyceride levels.
J A Sanchez-Izquierdo-Riera; R E Caballero-Cubedo; J L Perez-Vela; A Ambros-Checa; J A Cantalapiedra-Santiago; E Alted-Lopez
Related Documents :
14720528 - Overweight and obesity in patients with established coronary heart disease: are we meet...
2191018 - Plasma catecholamine concentration during sedation in ventilated patients requiring int...
6805358 - Disoprofol and fentanyl for total intravenous anaesthesia.
424108 - The effect of internal fetal monitoring on cesarean section morbidity.
24535378 - Overweight is associated with improved survival and outcomes in patients with atrial fi...
23821288 - Relationship between estimated glomerular filtration rate and biological half-life of 1...
Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Anesthesia and analgesia     Volume:  86     ISSN:  0003-2999     ISO Abbreviation:  Anesth. Analg.     Publication Date:  1998 Jun 
Date Detail:
Created Date:  1998-06-19     Completed Date:  1998-06-19     Revised Date:  2014-07-29    
Medline Journal Info:
Nlm Unique ID:  1310650     Medline TA:  Anesth Analg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1219-24     Citation Subset:  AIM; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Analgesics, Opioid / therapeutic use
Anesthesia Recovery Period
Blood Pressure / drug effects
Brain / drug effects,  physiology
Craniocerebral Trauma / therapy*
Drug Combinations
Heart Rate / drug effects
Hemodynamics / drug effects
Hypnotics and Sedatives / administration & dosage,  adverse effects,  therapeutic use*
Infusions, Intravenous
Intracranial Pressure / drug effects
Jugular Veins
Midazolam / administration & dosage*,  adverse effects,  therapeutic use*
Morphine / therapeutic use
Oxygen / blood
Propofol / administration & dosage,  adverse effects,  therapeutic use*
Prospective Studies
Respiration, Artificial
Triglycerides / blood
Wounds and Injuries / therapy*
Reg. No./Substance:
0/Analgesics, Opioid; 0/Drug Combinations; 0/Hypnotics and Sedatives; 0/Triglycerides; 76I7G6D29C/Morphine; R60L0SM5BC/Midazolam; S88TT14065/Oxygen; YI7VU623SF/Propofol
Comment In:
Anesth Analg. 1999 Nov;89(5):1329-30   [PMID:  10553870 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  The effects of general versus epidural anesthesia for outpatient extracorporeal shock wave lithotrip...
Next Document:  0.45% saline and 5% dextrose in water, but not 0.9% saline or 5% dextrose in 0.9% saline, worsen bra...