| Propofol versus halothane in paediatric daycase surgery: a comparison of the duration of induction and haemodynamic profile. | |
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MedLine Citation:
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PMID: 21913547 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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BACKGROUND: Inhalational induction with Halothane is commonly used for anaesthesia in children. Its drawbacks include bradycardia and hypotension. Intravenous propofol has recently challenged this position. OBJECTIVE: This study sought to compare duration of and cardiovascular changes at induction of anaesthesia in children. METHODS: Sixty ASA I and II children aged 1- 7 years scheduled for elective daycase surgery were prospectively studied from January to July 2008. They were assigned to receive inhalational induction with halothane 3% or intravenous induction with 3.5mg/kg of propofol. Heart rate, systolic, diastolic and mean blood pressure as well as oxygen saturation were monitored throughout induction. The duration of induction as well as any complications were documented. RESULTS: Demographic data was comparable between the two groups. Duration of induction was significantly longer in the halothane group 8.23 +/- 2.34 minutes compared with 2.30 +/- 1.26 minutes in the propofol group (p < 0.001). Heart rate rose by 4.7 +/- 17.73 beats/minute in the propofol group and fell by 4.19 +/- 18.03 in the halothane group (p = 0.05). Systolic, diastolic and mean blood pressures fell in both groups with values being less in the halothane group. These differences were not significantly different (p = 0.189, p = 0.059, p = 0.058 respectively). Sixteen patients (33%) in the propofol group developed apnoea compared to 2 (6.6%) in the halothane group (p < 0.001). The duration of apnoea differed significantly between groups (p = 0.003). CONCLUSION: Halothane and propofol had similar changes to cardiovascular parameters during anaesthetic induction. The shorter duration of induction of propofol may be preferable for daycase surgeries. |
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Authors:
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M O Akintimoye; I Desalu; O T Kushimo |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Nigerian quarterly journal of hospital medicine Volume: 21 ISSN: 0189-2657 ISO Abbreviation: Nig Q J Hosp Med Publication Date: 2011 Jan-Mar |
Date Detail:
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Created Date: 2011-09-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9713944 Medline TA: Nig Q J Hosp Med Country: Nigeria |
Other Details:
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Languages: eng Pagination: 80-4 Citation Subset: IM |
Affiliation:
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Dept. of Anaesthesia, General Hospital, Isolo. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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