Document Detail

Propofol--a safe and effective sedative for endoscopy.
MedLine Citation:
PMID:  12696824     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Propofol has recently been reported to be a safe sedative for endoscopy. METHODS: One hundred consecutive patients more than 18 years of age undergoing an endoscopic procedure were included in the study. The risk of sedation was calculated using the American Society of Anesthesiology risk class. Pregnant women, patients opting to undergo endoscopy without sedation, and those allergic to any sedative, eggs or soyabeans were excluded. A trained nurse administered propofol under the supervision of an anesthesiologist. Vital parameters, including oxygen saturation, were measured before and during the procedure. Time taken for full sedation, quantity of propofol used, duration of the procedure, time taken for recovery from sedation, and any complication during or after anesthesia were recorded. The patients scored quality of sedation, perception of pain and any memory of the procedure. RESULTS: Eighty-four patients were in ASA risk class I and II and the remaining 16 were in a higher ASA risk class. There was no difference in vital sign measurements during the endoscopic procedures as compared to baseline values. None of the patients had any complication. More than 90% of patients did not report any pain and had complete amnesia for the procedure. CONCLUSION: Propofol is a safe and effective sedative for endoscopic procedures.
Sudeep Khanna; Raj Tobin; Sanjay Khare; Jagdish Vij; Arun Kumar
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology     Volume:  22     ISSN:  0254-8860     ISO Abbreviation:  Indian J Gastroenterol     Publication Date:    2003 Mar-Apr
Date Detail:
Created Date:  2003-04-16     Completed Date:  2003-05-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8409436     Medline TA:  Indian J Gastroenterol     Country:  India    
Other Details:
Languages:  eng     Pagination:  56-8     Citation Subset:  IM    
Department of Gastroenterology, Pushpawati Singhania Research Institute for Liver, Renal and Digestive Diseases, New Delhi 110 017.
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MeSH Terms
Aged, 80 and over
Endoscopy, Gastrointestinal*
Hypnotics and Sedatives*
Middle Aged
Prospective Studies
Reg. No./Substance:
0/Hypnotics and Sedatives; 2078-54-8/Propofol

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