Document Detail

Propofol-related infusion syndrome induced by "moderate dosage" in a patient with severe head trauma.
MedLine Citation:
PMID:  22284319     Owner:  NLM     Status:  In-Data-Review    
Propofol is widely used for sedating critically ill adult patients because of its rapid onset and short recovery times, even after prolonged use. Propofol may be associated with a life-threatening syndrome, propofol-related infusion syndrome (PRIS), which includes cardiac failure, severe metabolic acidosis, renal failure, and rhabodomyolysis. The pathophysiology is incompletely understood. Propofol-related infusion syndrome seems to be dose-related, and it occurs generally in patients undergoing long-term (> 48 hrs) sedation at higher doses (> 4 mg/kg/hr). A case of PRIS in a patient after severe head injury is presented.
Thorsten Annecke; Peter Conzen; Ludwig Ney
Related Documents :
22349879 - Entheseal ultrasound abnormalities in patients with sapho syndrome.
24283689 - Chorea and high antiphospholipid antibodies: probable primary antiphospholipid syndrome.
25117419 - Evaluation of basal ganglia and thalamic inflammation in children with pediatric autoim...
22607519 - Macrophage activation syndrome in a patient with pulmonary inflammatory myofibroblastic...
22901909 - The role of bronchoscopy in the management of patients with severe craniofacial syndromes.
1495739 - Meigs syndrome with elevated serum ca 125.
10863169 - Metabolic syndrome x: a review.
24626939 - Sjögren's syndrome: an underdiagnosed condition in mixed connective tissue disease.
7069429 - Dysaesthesias and dysautonomia: a self-limited syndrome of painful dysaesthesias and au...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of clinical anesthesia     Volume:  24     ISSN:  1873-4529     ISO Abbreviation:  J Clin Anesth     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-01-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8812166     Medline TA:  J Clin Anesth     Country:  United States    
Other Details:
Languages:  eng     Pagination:  51-4     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Nerve stimulator versus ultrasound guidance for placement of popliteal catheters for foot and ankle ...
Next Document:  Noninvasive positive pressure ventilation in the management of acute respiratory failure due to oste...