| Propofol-related infusion syndrome induced by "moderate dosage" in a patient with severe head trauma. | |
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MedLine Citation:
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PMID: 22284319 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Propofol is widely used for sedating critically ill adult patients because of its rapid onset and short recovery times, even after prolonged use. Propofol may be associated with a life-threatening syndrome, propofol-related infusion syndrome (PRIS), which includes cardiac failure, severe metabolic acidosis, renal failure, and rhabodomyolysis. The pathophysiology is incompletely understood. Propofol-related infusion syndrome seems to be dose-related, and it occurs generally in patients undergoing long-term (> 48 hrs) sedation at higher doses (> 4 mg/kg/hr). A case of PRIS in a patient after severe head injury is presented. |
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Authors:
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Thorsten Annecke; Peter Conzen; Ludwig Ney |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of clinical anesthesia Volume: 24 ISSN: 1873-4529 ISO Abbreviation: J Clin Anesth Publication Date: 2012 Feb |
Date Detail:
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Created Date: 2012-01-30 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8812166 Medline TA: J Clin Anesth Country: United States |
Other Details:
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Languages: eng Pagination: 51-4 Citation Subset: IM |
Copyright Information:
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Copyright © 2012 Elsevier Inc. All rights reserved. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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