Document Detail


Propofol lipemia mimicking chyle leak during neck dissection.
MedLine Citation:
PMID:  16983690     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Propofol is an intravenous agent used in anesthesia. Lipemia is an uncommon adverse effect of propofol infusion. METHODS: A patient undergoing neck dissection for recurrent chordoma had intraoperative lipemia develop after prolonged propofol infusion. RESULTS: Lipemia gave blood in the surgical field a milky appearance resembling chyle, but no chyle leak was present. Lipemia was confirmed by drawing a sample of blood and leaving it to stand. Layering of the blood with a milky white upper layer was observed. Analysis of a second sample of blood revealed a high lipemic index. CONCLUSIONS: Lipemia is an uncommon adverse effect of propofol infusion, which may give blood a milky appearance and be confused for a chyle leak in a dissected neck. Identification of lipemia is also important because there is a risk of acute pancreatitis, and it may represent the early stage of propofol infusion syndrome.
Authors:
David E Vokes; Mark E Linskey; William B Armstrong
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Head & neck     Volume:  28     ISSN:  1043-3074     ISO Abbreviation:  Head Neck     Publication Date:  2006 Dec 
Date Detail:
Created Date:  2006-11-23     Completed Date:  2007-01-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8902541     Medline TA:  Head Neck     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1147-9     Citation Subset:  IM    
Affiliation:
Department of Otolaryngology-Head & Neck Surgery, University of California Irvine Medical Center, 101 The City Drive South, Building 56, Suite 500, Orange, California 92868, USA. dvokes@uci.edu
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MeSH Terms
Descriptor/Qualifier:
Anesthetics, Intravenous / adverse effects*
Chyle*
Diagnosis, Differential
Humans
Hyperlipidemias / chemically induced*,  diagnosis*
Intraoperative Complications
Male
Middle Aged
Neck Dissection / adverse effects*
Propofol / adverse effects*
Chemical
Reg. No./Substance:
0/Anesthetics, Intravenous; 2078-54-8/Propofol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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