Document Detail

Propofol anesthesia enhances pressor response to ephedrine in patients given clonidine.
MedLine Citation:
PMID:  10389775     Owner:  NLM     Status:  MEDLINE    
IMPLICATIONS: We evaluated the pressor response to ephedrine during isoflurane or propofol anesthesia with or without clonidine premedication. Our study suggests that, in anesthetized patients premedicated with clonidine, decreases in blood pressure may be easier to reverse with ephedrine with some types of anesthesia (e.g., propofol) than with others (e.g., isoflurane).
Y Hayakawa-Fujii; H Iida; S Dohi
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Anesthesia and analgesia     Volume:  89     ISSN:  0003-2999     ISO Abbreviation:  Anesth. Analg.     Publication Date:  1999 Jul 
Date Detail:
Created Date:  1999-07-20     Completed Date:  1999-07-20     Revised Date:  2013-05-20    
Medline Journal Info:
Nlm Unique ID:  1310650     Medline TA:  Anesth Analg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  37-41     Citation Subset:  AIM; IM    
Department of Anesthesiology and Critical Care Medicine, Gifu University School of Medicine, Gifu City, Japan.
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MeSH Terms
Anesthetics, Intravenous / pharmacology*
Blood Pressure / drug effects*
Clonidine / pharmacology*
Ephedrine / pharmacology*
Heart Rate / drug effects
Middle Aged
Preanesthetic Medication*
Propofol / pharmacology*
Reg. No./Substance:
0/Anesthetics, Intravenous; 2078-54-8/Propofol; 299-42-3/Ephedrine; 4205-90-7/Clonidine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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