Document Detail

Prophylactic treatment of venous thromboembolic disease in palliative care. A survey about four different clinical cases
MedLine Citation:
PMID:  19375271     Owner:  NLM     Status:  MEDLINE    
There are no specific studies evaluating the benefit/risk of antithrombotic prophylactic treatment in patients hospitalised in a palliative care unit. So, the aim of this study was to evaluate the clinicians attitudes about antithrombotic prophylaxis for patients in palliative care units and the elements which determined their decisions. METHODS: The clinical data of 4 terminally ill patients were extracted from database of a Palliative Care Unit in France. These 4 patients were selected as they represented several different situations according to the presence or not of major thrombotic risk factors, bleeding risk factors, and request of compassionate care. Through an open questionnaire, fourteen clinicians usually in charge of palliative care patients were individually interviewed about antithrombotic prophylactic therapy for each case of patients. RESULTS: except in the case of a patient with major thrombotic risk factors, no bleeding risk factor and wishing to receive active care, both the attitudes of clinicians to initiate or continue a prophylactic therapy and the elements which lead to their decisions were heterogeneous at least. CONCLUSION: the absence of recommendations based on validated clinical trials evaluating the efficacy and safety of thromboembolism prophylactic treatment in palliative care patients lead to uncertain decisions for clinicians. Added to an objective evaluation of thrombotic and hemorrhagic risks factors, the wish of patient to receive or not active care is probably the most important element to consider.
Catherine Duverger; Bernard Tardy; Anne Richard; Thomas C??larier; Sophie Bayle; Marie Cambou; Jean Luc Perrot; Pascal Cathebras; Regis Gonthier;
Publication Detail:
Type:  English Abstract; Journal Article     Date:  2009-04-16
Journal Detail:
Title:  Presse m??dicale (Paris, France : 1983)     Volume:  38     ISSN:  0755-4982     ISO Abbreviation:  -     Publication Date:  2009 Sep 
Date Detail:
Created Date:  2009-09-08     Completed Date:  2009-09-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8302490     Medline TA:  Presse Med     Country:  France    
Other Details:
Languages:  fre     Pagination:  1235-9     Citation Subset:  IM    
Service de Soins Palliatifs, CHU Saint-Etienne, Saint-Etienne, France.
Vernacular Title:
Traitement prophylactique de la maladie thromboembolique veineuse en soins palliatifs. H??t??rog??n??it?? des pratiques des m??decins en r??ponse ?? 4 situations cliniques diff??rentes.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Attitude of Health Personnel*
Fibrinolytic Agents / administration & dosage
Middle Aged
Palliative Care*
Refusal to Treat
Risk Factors
Terminal Care
Treatment Refusal
Venous Thromboembolism / etiology,  prevention & control*
Reg. No./Substance:
0/Fibrinolytic Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Evaluation of ischemia-modified albumin in myocardial infarction and prostatic diseases.
Next Document:  Frequency of long-acting opioid analgesic initiation in opioid-naïve nursing home residents.