| Prophylactic methicillin for shunt operations: effects on incidence of shunt malfunction and infection. | |
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MedLine Citation:
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PMID: 7037325 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In a double-blind study, 74 children were randomly treated with prophylactic methicillin at the time of ventriculo-peritoneal shunting. There were 7 infections in the placebo group and 2 in the methicillin-treated group. There was no statistically significant difference in infection or overall malfunction rate between the two groups. The risk of shunt malfunction in the 2nd to 6th month after surgery was significantly greater in the placebo group (7 of 26 patients) than in the methicillin-treated group (1 of 26 patients). Delayed shunt malfunction may be prevented by a short course of perioperative antibiotics. |
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Authors:
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S J Haines; F Taylor |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Child's brain Volume: 9 ISSN: 0302-2803 ISO Abbreviation: Childs Brain Publication Date: 1982 |
Date Detail:
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Created Date: 1982-05-27 Completed Date: 1982-05-27 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7505428 Medline TA: Childs Brain Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 10-22 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Age Factors Bacterial Infections / etiology, prevention & control* Cerebrospinal Fluid Shunts / adverse effects* Child Child, Preschool Clinical Trials as Topic Double-Blind Method Equipment Failure Humans Infant Methicillin / therapeutic use* Random Allocation Risk |
| Chemical | |
Reg. No./Substance:
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61-32-5/Methicillin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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