Document Detail

Prophylactic lignocaine and early post-coronary artery occlusion dysrhythmias in anaesthetized greyhounds.
MedLine Citation:
PMID:  7470764     Owner:  NLM     Status:  MEDLINE    
1. Lignocaine (1 mg kg-1 min-1 infused intravenously for 30 min) greatly reduced the incidence of ventricular ectopic beats that resulted from acute coronary artery ligation in anaesthetized greyhound dogs. However, the incidence of ventricular fibrillation was only slightly reduced by this treatment which caused significant myocardial depression. 2. There is no good evidence from this study that lignocaine is a particularly effective prophylactic in acute myocardial infarction.
R J Marshall; J R Parratt
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British journal of pharmacology     Volume:  71     ISSN:  0007-1188     ISO Abbreviation:  Br. J. Pharmacol.     Publication Date:  1980  
Date Detail:
Created Date:  1981-05-13     Completed Date:  1981-05-13     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  7502536     Medline TA:  Br J Pharmacol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  597-600     Citation Subset:  IM    
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MeSH Terms
Arrhythmias, Cardiac / etiology,  prevention & control*
Coronary Vessels / physiology
Disease Models, Animal
Hemodynamics / drug effects
Lidocaine / therapeutic use*
Myocardial Infarction / complications*
Reg. No./Substance:

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