Document Detail

Prophylactic digitalisation in pulmonary surgery.
MedLine Citation:
PMID:  1539143     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Prophylactic digoxin is widely used in patients undergoing pulmonary surgery to prevent or control cardiac arrhythmias, but whether it is helpful or not is uncertain. METHODS: An open, controlled randomised prospective clinical study of 111 patients was undertaken to compare the incidence of cardiac arrhythmias in the 58 patients who received preoperative digoxin and the 53 who did not. RESULTS: Cardiac arrhythmia occurred in half (29/58) of those given prophylactic digoxin and in 36% (19/53) of those who were not. The overall incidence of arrhythmia was 43%, with no statistically significant difference between the groups. CONCLUSION: Cardiac arrhythmias remain an important complication of pulmonary surgery and the incidence is not reduced by prophylactic digoxin.
A J Ritchie; M Danton; J R Gibbons
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Thorax     Volume:  47     ISSN:  0040-6376     ISO Abbreviation:  Thorax     Publication Date:  1992 Jan 
Date Detail:
Created Date:  1992-04-02     Completed Date:  1992-04-02     Revised Date:  2010-09-07    
Medline Journal Info:
Nlm Unique ID:  0417353     Medline TA:  Thorax     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  41-3     Citation Subset:  IM    
Department of Cardiothoracic Surgery, Royal Victoria Hospital, Belfast.
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MeSH Terms
Arrhythmias, Cardiac / epidemiology,  prevention & control*
Digoxin / therapeutic use*
Intraoperative Complications / epidemiology,  prevention & control*
Lung / surgery*
Middle Aged
Postoperative Period
Prospective Studies
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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