Document Detail

Prophylactic ciprofloxacin drops after tympanostomy tube insertion.
MedLine Citation:
PMID:  14758376     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To evaluate the effectiveness of prophylactic ciprofloxacin drops in decreasing the incidence of post-tympanostomy otorrhea, and the relation between middle ear content and post-tympanostomy otorrhea. METHODS: One hundred and fifty patients aged 3-14 years underwent tympanostomy and tube insertion at the Prince Rashid Ben Al-Hasan Hospital, Al-Husn, Jordan during the interval between February 2000 to January 2003. The patients were randomized into 3 groups: group 1 (control group) received no antibiotic drops, group 2 received a single dose of ciprofloxacin drops intraoperatively and group 3 received an intraoperative dose followed by 5-day postoperative course. RESULTS: Application of topical ciprofloxacin after tympanostomy tube insertion was associated with a significantly lower incidence of early post-tympanostomy otorrhea. The rate of otorrhea for the control group was 16.5% and the treatment groups were (group 1) 8.4%, (group 2) 8.2% and p=0.011. A single dose of antibiotics was effective when patient's middle ears were dry or had serous effusions. For those whose ears had mucoid or purulent content a 5-day course was indicated. CONCLUSION: Topical administration of a single dose of ototopical ciprofloxacin after surgery is an effective treatment for the prevention of early post-tympanostomy otorrhea, and a prolonged course (5 days) may be indicated for those whose ears had purulent or thick mucoid contents, and the content of middle ear are important in predicating postoperative otorrhea.
Omer Nawasreh; Ibrahim A Al-Wedyan
Related Documents :
10363736 - Loracarbef versus clarithromycin in children with acute otitis media with effusion.
22122536 - Interpersonal styles of chronically depressed outpatients: profiles and therapeutic cha...
7524796 - Efficacy and safety of piperacillin/tazobactam in skin and soft tissue infections.
2149046 - Teicoplanin in the treatment of gram-positive bacteraemia in neutropenic patients.
18298356 - A high-intensity lumbar extensor strengthening program is little better than a low-inte...
843186 - Symptom change and prognosis in clinic psychotherapy.
Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Saudi medical journal     Volume:  25     ISSN:  0379-5284     ISO Abbreviation:  Saudi Med J     Publication Date:  2004 Jan 
Date Detail:
Created Date:  2004-02-03     Completed Date:  2004-10-05     Revised Date:  2008-06-23    
Medline Journal Info:
Nlm Unique ID:  7909441     Medline TA:  Saudi Med J     Country:  Saudi Arabia    
Other Details:
Languages:  eng     Pagination:  38-40     Citation Subset:  IM    
Department of Otolaryngology, Prince Rashid Ben Al-Husn Hospital, Jordan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Administration, Topical
Antibiotic Prophylaxis*
Child, Preschool
Ciprofloxacin / administration & dosage*
Follow-Up Studies
Intraoperative Care
Middle Ear Ventilation / adverse effects,  methods*
Otitis Media with Effusion / diagnosis,  surgery*
Postoperative Care
Postoperative Complications / prevention & control
Reference Values
Risk Assessment
Treatment Outcome
Reg. No./Substance:
0/Solutions; 85721-33-1/Ciprofloxacin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Intestinal parasites among presumably healthy individuals in Lebanon.
Next Document:  Ultrasonography of the uterus after normal vaginal delivery.