| Prophylactic anticoagulation following acute myocardial infarction. | |
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MedLine Citation:
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PMID: 3513727 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Although several large trials have failed to demonstrate unequivocally that anticoagulation decreases mortality following myocardial infarction (MI), anticoagulation has been advocated to prevent embolic cerebrovascular accidents (CVAs). Since CVAs occur during hospitalization in only 1.5% to 3% of MIs, it is not justifiable to anticoagulate all patients after MI because the risk of anticoagulation exceeds the potential benefit. However, a group of patients who are at high risk of developing left ventricular thrombi (LVT) and CVA following MI can be identified. Thirty percent to 40% of patients with transmural anterior MI develop LVT, and early anticoagulation with heparin sodium prevents LVT formation and CVAs in this group. A two-dimensional echocardiogram before hospital discharge allows the identification of patients at risk for later embolization and helps determine the need for anticoagulation with warfarin sodium following hospitalization. |
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Authors:
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K Kaplan |
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9538317 - Left atrial thrombus as an early consequence of blunt chest trauma. 19689257 - Anticoagulation in patients with heart failure. 12354367 - Long-term anticoagulation therapy in prevention of stroke. 2391307 - Locked in state. a clinicopathological study. 3794577 - Second degree type ii and complete atrioventricular block due to hyperkalemia. 22437127 - Paracardioscopy provides endoscopic visualization of the heart. |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Archives of internal medicine Volume: 146 ISSN: 0003-9926 ISO Abbreviation: Arch. Intern. Med. Publication Date: 1986 Mar |
Date Detail:
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Created Date: 1986-03-28 Completed Date: 1986-03-28 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0372440 Medline TA: Arch Intern Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 593-7 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Cardiovascular Diseases
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etiology*,
mortality,
prevention & control Echocardiography Heart Diseases / prevention & control Heparin / therapeutic use Humans Length of Stay Myocardial Infarction / complications* Risk Thrombosis / prevention & control Warfarin / therapeutic use |
| Chemical | |
Reg. No./Substance:
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81-81-2/Warfarin; 9005-49-6/Heparin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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