Document Detail


Prophylactic amnioinfusion in pregnancies complicated by oligohydramnios: a prospective study.
MedLine Citation:
PMID:  2014078     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Prophylactic amnioinfusion was assessed in term and post-dates pregnancies with decreased amniotic fluid volume. Subjects were randomly assigned to one of three groups: amnioinfusion with warmed saline solution, room-temperature saline, or control. Patients receiving prophylactic amnioinfusion had a significant decrease in both the frequency and severity of variable decelerations in the first stage of labor (P = .006) and in the average total number of variable decelerations in the first and second stages of labor (P = .01) compared with controls. There was no observed effect on newborn serum electrolyte levels with amnioinfusion, nor was there any apparent benefit of infusion of warmed saline compared with room-temperature saline. In contrast to premature gestations with oligohydramnios, prophylactic amnioinfusion was not associated with a significant improvement in mean umbilical arterial and venous pH or a significant decrease in cesarean delivery for fetal distress (P = .09). This is perhaps because the term fetus has an enhanced ability to tolerate recurrent episodes of heart rate decelerations without demonstrating the rapid metabolic changes seen in the premature fetus.
Authors:
M P Nageotte; L Bertucci; C V Towers; D L Lagrew; H Modanlou
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  77     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  1991 May 
Date Detail:
Created Date:  1991-05-15     Completed Date:  1991-05-15     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  677-80     Citation Subset:  AIM; IM    
Affiliation:
Women's Hospital Long Beach Memorial Medical Center, California.
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MeSH Terms
Descriptor/Qualifier:
Adult
Female
Fetal Growth Retardation / complications*
Gestational Age
Heart Rate, Fetal
Hot Temperature
Humans
Labor, Obstetric
Oligohydramnios / complications*,  therapy*
Pregnancy
Pregnancy, Prolonged*
Prospective Studies
Sodium Chloride / administration & dosage*
Chemical
Reg. No./Substance:
7647-14-5/Sodium Chloride

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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