Document Detail

Properties of maedi nucleic acid and the presence of ribonucleic acid- and deoxyribonucleic acid-dependent deoxyribonucleic acid polymerase in the virions.
MedLine Citation:
PMID:  4116344     Owner:  NLM     Status:  MEDLINE    
Maedi virus contains a ribonucleic acid (RNA) which can be resolved into three major components, namely, 62S, 33S, and 13S, by sucrose gradient centrifugation. The presence of RNA- and deoxyribonucleic acid (DNA)-dependent DNA polymerase in virions of maedi virus was demonstrated. The enzyme product could be converted into acid-soluble form by pancreatic deoxyribonuclease, but was resistant to digestion by pancreatic ribonuclease and to hydrolysis by NaOH.
F H Lin; H Thormar
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of virology     Volume:  10     ISSN:  0022-538X     ISO Abbreviation:  J. Virol.     Publication Date:  1972 Aug 
Date Detail:
Created Date:  1972-11-19     Completed Date:  1972-11-19     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0113724     Medline TA:  J Virol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  228-33     Citation Subset:  IM    
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MeSH Terms
Centrifugation, Density Gradient
Choroid Plexus
Culture Techniques
DNA, Viral / biosynthesis
Pulmonary Adenomatosis, Ovine / microbiology
RNA, Viral / analysis*,  isolation & purification
RNA-Directed DNA Polymerase / analysis*,  metabolism
Sodium Hydroxide
Thymidine / metabolism
Thymine Nucleotides / metabolism
Uridine / metabolism
Viruses, Unclassified / analysis*,  enzymology,  growth & development,  metabolism
Reg. No./Substance:
0/DNA, Viral; 0/RNA, Viral; 0/Thymine Nucleotides; 10028-17-8/Tritium; 1310-73-2/Sodium Hydroxide; 50-89-5/Thymidine; 58-96-8/Uridine; EC DNA Polymerase; EC 3.1.-/Ribonucleases

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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