Document Detail


Properties of the ON bistratified ganglion cell in the rabbit retina.
MedLine Citation:
PMID:  23047654     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The identity of the types of different neurons in mammalian retinae is now close to being completely known for a few mammalian species; comparison reveals strong homologies for many neurons across the order. Still, there remain some cell types rarely encountered and inadequately described, despite not being rare in relative frequency. Here we describe in detail an additional ganglion cell type in rabbit that is bistratified with dendrites in both sublaminae, yet spikes only at light onset and has no response bias to the direction of moving bars. This ON bistratified ganglion cell type is most easily distinguished by the unusual behavior of its dendritic arbors. While dendrites that arborize in sublamina b terminate at that level, those that ascend to arborize in sublamina a do not normally terminate there. Instead, when they reach the approximate radius of the dendrites in sublamina b, they dive sharply back down to ramify in sublamina b. Here they continue to course even further away from the soma at the same level as the branches wholly contained in sublamina b, thereby forming an annulus of secondary ON dendrites in sublamina b. This pattern of branching creates a bistratified dendritic field of approximately equal area in the two sublaminae initially, to which is then added an external annulus of dendrites only in sublamina b whose origin is entirely from processes descending from sublamina a. It is coupled to a population of wide-field amacrine cells upon which the dendrites of the ganglion cell often terminate.
Authors:
Hideo Hoshi; Lian-Ming Tian; Stephen C Massey; Stephen L Mills
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of comparative neurology     Volume:  521     ISSN:  1096-9861     ISO Abbreviation:  J. Comp. Neurol.     Publication Date:  2013 May 
Date Detail:
Created Date:  2013-03-19     Completed Date:  2013-08-26     Revised Date:  2014-05-08    
Medline Journal Info:
Nlm Unique ID:  0406041     Medline TA:  J Comp Neurol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1497-509     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Wiley Periodicals, Inc.
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MeSH Terms
Descriptor/Qualifier:
Animals
Electrophysiology
Immunohistochemistry
Microscopy, Confocal
Rabbits
Retinal Ganglion Cells / physiology*,  ultrastructure*
Grant Support
ID/Acronym/Agency:
EY06515/EY/NEI NIH HHS; EY10121/EY/NEI NIH HHS; EY10608/EY/NEI NIH HHS; P30 EY010608/EY/NEI NIH HHS; R01 EY006515/EY/NEI NIH HHS; R01 EY010121/EY/NEI NIH HHS
Comments/Corrections

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