Document Detail

Proper use of skin tests with food extracts in diagnosis of hypersensitivity to food in children.
MedLine Citation:
PMID:  73429     Owner:  NLM     Status:  MEDLINE    
This study was undertaken to determine the proper use of skin tests with food extracts in diagnosis of hypersensitivity to food in children. Cutaneous reactions evoked by graded amounts of food extracts were compared with results of double-blind food challenge and in vitro release of histamine from leucocytes. A 3 mm or greater weal reaction in skin tests by puncture technique using food extracts of 1:20 w/v concentration was found to indicate the degree of hypersensitivity likely to be associated with clinically significant hypersensitivity reactions to food. Proper use of this simple technique will facilitate accurate diagnosis of food hypersensitivity in children by identifying the group among whom all positive reactions to food challenges will be found. Nevertheless, double-blind food challenge is essential to establish a diagnosis of symptomatic hypersensitivity to food.
S A Bock; J Buckley; A Holst; C D May
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Publication Detail:
Type:  Clinical Trial; Controlled Clinical Trial; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Clinical allergy     Volume:  7     ISSN:  0009-9090     ISO Abbreviation:  Clin. Allergy     Publication Date:  1977 Jul 
Date Detail:
Created Date:  1978-02-18     Completed Date:  1978-02-18     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0311172     Medline TA:  Clin Allergy     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  375-83     Citation Subset:  IM    
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MeSH Terms
Arachis hypogaea / adverse effects
Asthma / complications
Child, Preschool
Clinical Trials as Topic
Eggs / adverse effects
Food Hypersensitivity / complications,  diagnosis*
Histamine Release
Leukocytes / immunology
Skin Tests

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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