Document Detail

Proper outcome measurements regarding glaucoma: the inadequacy of using intraocular pressure alone.
MedLine Citation:
PMID:  8823579     Owner:  NLM     Status:  MEDLINE    
Physicians typically assess glaucoma treatment in terms of the effect on intraocular pressure (IOP). However, it is inappropriate to use IOP as the sole outcome measure for the management of glaucoma for several reasons: a) it is a precursor of disease, but not the disease itself. b) Most often, it is not the only factor responsible for glaucomatous damage. c) It suggests, wrongly, that IOP should be maximally lowered in all glaucoma patients. d) We are beginning to be able to assess more accurately other signs, not just precursors, of glaucomatous damage itself, most importantly, optic disc damage and visual field loss. Even though these signs are far more valuable than IOP in assessing the outcome of treatment, they, too, nevertheless, are ultimately subordinate to the effect of treatment on the patient's quality of life.
G L Spaeth
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  European journal of ophthalmology     Volume:  6     ISSN:  1120-6721     ISO Abbreviation:  Eur J Ophthalmol     Publication Date:    1996 Apr-Jun
Date Detail:
Created Date:  1996-12-06     Completed Date:  1996-12-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9110772     Medline TA:  Eur J Ophthalmol     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  101-5     Citation Subset:  IM    
Glaucoma Service, Wills Eye Hospital, Philadelphia, PA, USA.
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MeSH Terms
Glaucoma / diagnosis,  physiopathology*,  therapy
Image Processing, Computer-Assisted
Intraocular Pressure*
Quality of Life
Treatment Outcome
Visual Acuity

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