| Propensity-score analysis of early outcomes after bilateral versus single internal thoracic artery grafting. | |
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MedLine Citation:
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PMID: 22436718 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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OBJECTIVE: : The use of bilateral internal thoracic arteries (BITAs) during coronary artery bypass grafting (CABG) improves long-term and event-free survival compared with single internal thoracic artery (SITA) grafting. It is controversial whether BITA grafting alters in-hospital adverse events after CABG. METHODS: : Isolated CABG cases using BITA or SITA at a single US academic center between January 1, 1997 and June 30, 2006 were retrospectively reviewed. A propensity score was used as a covariate to balance the treatment groups (BITA and SITA) with respect to 44 preoperative risk factors. A multivariable logistic regression model tested whether treatment type was significantly associated with in-hospital death, deep sternal wound infection (DSWI), or hospital length of stay (LOS). RESULTS: : There were 599 BITA and 10,212 SITA cases performed. Overall for all BITA versus SITA cases, adjusted mortality (0.8% vs. 1.7%, P = 0.85) was not different between the groups. However, adjusted incidence of DSWI (2.0% vs. 1.2%, P = 0.036) and LOS (6.7 vs. 6.1, P = 0.025) were significantly higher in BITA patients. Subsets analyses of obese patients and diabetic patients revealed no statistical differences for any of the outcomes between BITA and SITA. CONCLUSIONS: : The long-term benefits of BITA grafting do not come at the cost of increased adjusted risk of in-hospital death. BITA grafting was associated with an increased risk of DSWI and a longer adjusted LOS. Neither obesity, nor diabetes significantly increased the risk of poor outcomes after BITA. |
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Authors:
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Sorin V Pusca; Patrick D Kilgo; J David Vega; William A Cooper; Thomas A Vassiliades; Edward P Chen; Omar M Lattouf; Robert A Guyton; John D Puskas |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Innovations (Philadelphia, Pa.) Volume: 3 ISSN: 1556-9845 ISO Abbreviation: Innovations (Phila) Publication Date: 2008 Jan |
Date Detail:
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Created Date: 2012-03-22 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101257528 Medline TA: Innovations (Phila) Country: United States |
Other Details:
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Languages: eng Pagination: 19-24 Citation Subset: - |
Affiliation:
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From the *Clinical Research Unit, Division of Cardiothoracic Surgery, Emory University School of Medicine; and †Department of Biostatistics, Rollins School of Public Health, Emory University, Atlanta, Georgia. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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