Document Detail

Prooxidant-antioxidant balance in blood during the surgical treatment of obliterating arterial atherosclerosis in the lower extremities.
MedLine Citation:
PMID:  15631348     Owner:  NLM     Status:  MEDLINE    
The chronic disorder of arterial circulation in the lower extremities due to the atherosclerotic injuries of the femoral-popliteal-tibial arteries was accompanied by the shift of the blood prooxidant-antioxidant balance towards more active free radical oxidation and by a depletion of antioxidant system. After restoring arterial blood flow in the ischemic lower extremities this balance was shifted towards more prominent lipid peroxidation processes. Such pattern of prooxidant-antioxidant balance changes implicates the development of strategies for its correction targeted on the reduction of lipid peroxidation activity and therefore on a tissue defense against the reperfusion injury.
N N Ioskevich; V V Zinchuk
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Roczniki Akademii Medycznej w Białymstoku (1995)     Volume:  49     ISSN:  -     ISO Abbreviation:  Rocz. Akad. Med. Bialymst.     Publication Date:  2004  
Date Detail:
Created Date:  2005-01-05     Completed Date:  2005-03-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9515551     Medline TA:  Rocz Akad Med Bialymst     Country:  Poland    
Other Details:
Languages:  eng     Pagination:  222-6     Citation Subset:  IM    
Surgical Disease Department No 1, Grodno State Medical University, Belarus.
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MeSH Terms
Antioxidants / metabolism*
Arteriosclerosis Obliterans / blood*,  surgery*
Femoral Artery / surgery
Free Radicals / blood*
Ischemia / blood
Lipid Peroxidation
Popliteal Artery / surgery
Reperfusion Injury / blood*,  etiology
Tibial Arteries / surgery
Vascular Surgical Procedures*
Reg. No./Substance:
0/Antioxidants; 0/Free Radicals

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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