Document Detail


Promyelocytic sarcoma of the spine: a case report and review of the literature.
MedLine Citation:
PMID:  20339529     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Myeloid sarcoma (MS, previously named granulocytic sarcoma or chloroma) is a rare extramedullary tumour of immature myeloid cells. It can be present before, concurrently with, or after the diagnosis of acute myeloid leukemia. MS is extremely uncommon in acute promyelocytic leukemia (APL). In the case described here, MS was the sole site of APL relapse and the cause of spinal cord compression. The patient presented with neurologic symptoms due to a paravertebral mass of MS after 7 years of complete remission. He was treated with excision of the mass followed by local radiotherapy. Systemic treatment was also given with combined arsenic trioxide and all-trans retinoic acid and the patient was able to achieve a second prolonged clinical and molecular remission.
Authors:
Leonardo Pacilli; Francesco Lo Coco; Safaa Mahmoud Ramadan; Laura Giannì; Alberto Pingi; Daniele Remotti; Ignazio Majolino
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Publication Detail:
Type:  Journal Article     Date:  2010-03-18
Journal Detail:
Title:  Advances in hematology     Volume:  2010     ISSN:  1687-9112     ISO Abbreviation:  Adv Hematol     Publication Date:  2010  
Date Detail:
Created Date:  2010-03-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101504271     Medline TA:  Adv Hematol     Country:  Egypt    
Other Details:
Languages:  eng     Pagination:  137608     Citation Subset:  -    
Affiliation:
Hematology and BMT Unit, Institute of Hematotherapy, Ospedale S. Camillo, 00153 Rome, Italy.
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