| Promyelocytic sarcoma of the spine: a case report and review of the literature. | |
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MedLine Citation:
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PMID: 20339529 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Myeloid sarcoma (MS, previously named granulocytic sarcoma or chloroma) is a rare extramedullary tumour of immature myeloid cells. It can be present before, concurrently with, or after the diagnosis of acute myeloid leukemia. MS is extremely uncommon in acute promyelocytic leukemia (APL). In the case described here, MS was the sole site of APL relapse and the cause of spinal cord compression. The patient presented with neurologic symptoms due to a paravertebral mass of MS after 7 years of complete remission. He was treated with excision of the mass followed by local radiotherapy. Systemic treatment was also given with combined arsenic trioxide and all-trans retinoic acid and the patient was able to achieve a second prolonged clinical and molecular remission. |
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Authors:
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Leonardo Pacilli; Francesco Lo Coco; Safaa Mahmoud Ramadan; Laura Giannì; Alberto Pingi; Daniele Remotti; Ignazio Majolino |
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Publication Detail:
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Type: Journal Article Date: 2010-03-18 |
Journal Detail:
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Title: Advances in hematology Volume: 2010 ISSN: 1687-9112 ISO Abbreviation: Adv Hematol Publication Date: 2010 |
Date Detail:
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Created Date: 2010-03-26 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101504271 Medline TA: Adv Hematol Country: Egypt |
Other Details:
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Languages: eng Pagination: 137608 Citation Subset: - |
Affiliation:
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Hematology and BMT Unit, Institute of Hematotherapy, Ospedale S. Camillo, 00153 Rome, Italy. |
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